Protein Senior Scientist

Joynes & Hunt; Cambridgeshire and Peterborough; On-site; GBP 40,000 - 80,000; Full time

Job summary

An established industry player in biotechnology research is seeking a Senior Scientist to lead LC-MS activities for peptide and protein quantitation. This exciting role involves designing and developing innovative bioanalytical methods while ensuring compliance with regulatory standards. The ideal candidate will possess a strong background in protein chemistry and bioanalytical techniques, and will play a crucial role in mentoring junior staff. Join a dynamic team that values continuous improvement and the implementation of cutting-edge technologies to enhance service offerings in the pharmaceutical and diagnostics sectors.

Qualifications

• In-depth knowledge of LC-MS method development and troubleshooting.
• Experience in training and mentoring others in a scientific setting.

Responsibilities

• Design and develop quantitative LC-MS bioanalytical methods.
• Validate assays in line with regulatory guidance and internal SOPs.
• Provide troubleshooting support for methodologies and instrumentation.

Skills

Bioanalytical LC-MS method development

Protein/peptide analysis

Training and mentoring

Knowledge of GLP/GCP guidelines

High resolution mass spectrometry

Understanding of hybrid LC-MS techniques

Protein chemistry

Education

Degree in pharmaceutical science

Degree in chemistry

Degree in biochemistry

Degree in biological science

Job description

Protein Senior Scientist

Location: Cambridgeshire

Our Client is a fast growing, value driven CRO in the biotechnology research sector. They provide a high quality service to their customers in a number of industries including pharmaceuticals and diagnostics. Their values play a key role in the way they work and the high standard of the products they produce.

They are looking for a senior scientist to join their drugs development solutions team to lead LC-MS activities specifically for the quantitation of peptides and proteins within biological fluids.

Key responsibilities include:

1. Design and develop quantitative LC-MS bioanalytical methods
2. Validating assays in line with regulatory guidance and internal SOPs
3. Provide bioanalytical support in troubleshooting methodologies and instrumentation
4. Engaging in continuous improvement, investigating, and implementing new technologies to improve service offering

Skills Required:

1. Degree in pharmaceutical science, chemistry, biochemistry, biological science, or equivalent
2. An in-depth knowledge and experience in protein / peptide bioanalytical LC-MS method development and troubleshooting
3. Demonstrated experience in training and mentoring others
4. Familiarity with the GLP/GCP guidelines associated with bioanalytical work
5. Experience with high resolution mass spectrometry applied to proteins or peptides would be desirable
6. Understanding of hybrid LC-MS techniques and application of automated workflows would be desirable
7. Understanding of protein chemistry would be desirable