Protein Production & Characterization (RA/Scientist, entry)

ZipRecruiter; Cambridge; On-site; GBP 40,000 - 60,000; Full time

Job summary

A biotechnology firm is seeking a motivated candidate to enhance antibody expression and purification protocols. The ideal applicant will have a life science degree with relevant experience and a passion for problem-solving. This role involves developing workflows to characterize antibody designs collaboratively. A competitive salary and benefits package is offered, emphasizing growth and training.

Benefits

Fast-moving work environment

Impactful decision-making

Competitive salary and equity

Qualifications

• Experience in antibody expression and purification protocols is preferred.
• 1-2 years of research/industry experience are highly desirable.
• Aptitude for quickly solving problems with precision.

Responsibilities

• Develop high-throughput antibody expression protocols.
• Characterize antibodies for key biophysical traits.
• Improve molecular biology workflows.
• Collaborate with lab scientists for production and testing.

Skills

Molecular biology workflows

Antibody characterization

High-throughput techniques

Cloning and DNA sequencing

Problem-solving

Education

Life science-focused MS or BS

Job description

Overview

Nabla Bio is building AI capable of generating biomolecules on demand to probe and treat disease. By combining cutting-edge AI with experimental systems that reflect how drugs behave in humans, we’re designing new kinds of medicines — targeting biology conventional tools can’t reach, and in drug formats built for disease precision, safety, and human impact. Backed by premier investors like Radical and Khosla Ventures, we have forged significant partnerships with leading pharma companies such as AstraZeneca, Takeda, and Bristol Myers Squibb.

The Role

Fueled by partnerships and increasing demand for internal R&D, we will be looking to you to help scale our antibody expression, purification, and developability measurement pipeline and apply it toward solving hard antibody design problems. This will include:

• Developing high-throughput HEK and CHO-based antibody expression and purification protocols.
• Prioritizing top development candidates by characterizing antibodies for key biophysical traits, including but not limited to, affinity, cross-reactivity, stability, polyspecificity, aggregation, and hydrophobicity
• Performing and improving molecular biology workflows including cloning, PCR, Gibson/Golden Gate assembly, DNA sequencing, and bacterial transformation.
• Working together with our dry-lab and other wet-lab scientists to establish a rapid and seamless production and testing pipeline for characterizing machine learning generated antibody designs
• This role has a strong focus on process development and workflows.

Qualifications

You are a strong candidate if you have led successful multi-month/year projects featuring direct experience in the above.

• Life science-focused MS or BS with 1-2 years research/industry experience are highly desirable.
• You must like to work quickly with precision. High aptitude, tenacity, and the foundational knowledge to solve problems outside of your comfort zone is critical.
• We will invest heavily in training you, and are committed to helping you grow within Nabla and beyond.

What We Offer

• A fast-moving environment where you can build and ship tools that impact real drug programs
• A small, focused team where your scientific and engineering decisions have outsized impact
• Highly competitive salary, equity, and benefits package

Nabla Bio is an equal opportunity employer. We welcome applicants from all backgrounds and experiences, and strongly encourage candidates from underrepresented groups in science and technology to apply. Reach out at [e-mail].