Principal Statistician

Warman O’Brien; United Kingdom; Remote; GBP 70,000 - 90,000; Full time

Job summary

A leading global Pharma company is seeking a Principal Statistician for a pivotal role in clinical development. The position offers an opportunity to drive statistical methodologies and oversee regulatory interactions while enjoying a flexible, fully home-based work arrangement. Candidates should have a solid background in Biostatistics and proven leadership experience in statistical project delivery, accompanied by a competitive salary and advancement prospects.

Benefits

Healthy work-life balance

Flexible hours

Career advancement opportunities

Competitive salary

Annual bonus

Car allowance

Qualifications

• PhD or MSc in Biostatistics, Statistics or closely related field.
• Experience in Pharmaceutical, CRO, Academic or Healthcare setting.
• Strong proficiency in SAS (R preferred).
• Proven leadership across global studies and regulatory submissions.

Responsibilities

• Lead statistical input across global development programs.
• Drive execution of biomarker and PK/PD analyses.
• Shape global standards and elevate statistical practices.

Skills

SAS

R

Leadership

Biostatistics

Clinical Development

Education

PhD in Biostatistics

MSc in Statistics

Job description

Principal Statistician | Global Pharma | UK | Home Based |

Global Pharma recognised for its commitment to innovation and patient impact, is expanding rapidly in the UK. As part of this growth, the company is offering a rare opportunity for an experienced Principal Statistician to join them.

This is an organisation where excellence is not just expected, it’s cultivated. Known for its open, forward-thinking culture and genuine commitment to purpose-driven science, the company provides an environment that inspires, supports, and rewards. Every contribution here matters. Every voice is valued. And every project pushes the boundaries of what’s possible in modern medicine.

As a Principal Statistician at the heart of global clinical development and biomarker strategy, operating at a senior level, the position spans complex clinical studies, innovative exploratory research, and regulatory interactions. You will drive design, oversight, and delivery of statistical components across early and late-phase assets, incorporating biomarker, PK/PD, and real-world data.

What you will be doing:

• Lead statistical input across global development programs with full ownership of statistical deliverables
• Independently contribute to complex study designs, go/no-go decisions, and strategic development planning
• Drive execution of biomarker and PK/PD analyses, with visible input into regulatory interactions and publications
• Work across clinical and commercial functions, ensuring strategic alignment of statistical methodologies and outcomes
• Shape global standards and elevate best-in-class statistical practices across the organisation

What you will need:

• PhD or MSc in Biostatistics, Statistics or a closely related field
• Experience in a Pharmaceutical, CRO, Academic or Healthcare setting
• Strong proficiency in SAS (R preferred
• Proven leadership across global studies, regulatory submissions, or health technology assessments
• High-level understanding of clinical development, data management, and regulatory/statistical guidelines

What’s in it for you:

• Enjoy a healthy work-life balance with flexible hours that fit your lifestyle
• Be part of an organisation dedicated to creating an inspiring and progressive workplace
• Unlock exciting career advancement opportunities with clear pathways for growth
• Benefit from a competitive salary, annual bonus, and a car allowance
• Fully home based in the UK

What to do next:

• If this opportunity is of interest, please apply now with your CV as the organisation are looking to arrange interviews for thePrincipal Statistician as soon as possible.

Not what you’re looking for?

• Please contact Jo Fornaciari on [phone] for a confidential discussion about potential opportunities.