Principal Scientist (Team Manager)

JR United Kingdom; Grangemouth; On-site; GBP 50,000 - 90,000; Full time

Job summary

An innovative firm is seeking a Principal Scientist to lead a talented team in developing life-saving pharmaceuticals. This role combines technical expertise with leadership, focusing on method development and project management. You'll work on exciting projects involving Antibody-Drug Conjugates, ensuring regulatory compliance and delivering on time. Join a dedicated team committed to improving patient outcomes while enhancing your career in a supportive environment. If you have a strong background in bioconjugation and a passion for mentoring, this is the perfect opportunity for you.

Qualifications

• Strong technical background in bioconjugation programs.
• Proven leadership skills in managing a team of scientists.

Responsibilities

• Lead method development and validation for lab-scale to toxicology projects.
• Ensure project deliverables meet objectives and timelines.
• Mentor scientists and handle line management responsibilities.

Skills

Protein modification

Conjugation chemistry

ADC purification

Process robustness

Analytical characterization of bioconjugates

Data interpretation

Collaboration skills

Job description

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Principal Scientist (Team Manager), Grangemouth

Client:

Piramal Pharma Solutions

Location:

Grangemouth, United Kingdom

Job Category:

Other

-

EU work permit required:

Yes

Job Views:

3

Posted:

05.05.2025

Expiry Date:

19.06.2025

Job Description:

Piramal is seeking a Team-leader/Principal Development Scientist responsible for leading method development, validation, and serving as the technical lead for projects ranging from lab-scale to toxicology development and pre-GMP technology transfer. The role involves both technical expertise and team leadership. The ideal candidate will have a strong technical background and proven (or potential) leadership skills in managing a team of scientists. Demonstrated ability to deliver project commitments on schedule is essential.

You will have the opportunity to work with a highly skilled team dedicated to bringing Antibody-Drug Conjugates to patients. We pride ourselves on serving our customers and patients by developing and manufacturing innovative, life-saving pharmaceuticals.

The Role:

Chief Accountabilities & Responsibilities

• Daily Work:
• Ensure project deliverables meet objectives and timelines.
• Provide technical support for manufacturing activities related to developed or transferred processes.
• Report analytical and process conclusions.
• Lead a small development team across multiple projects daily.
• Mentor scientists and handle line management responsibilities.

Quality:

• Follow protocols and procedures.
• Improve and challenge quality systems and procedures, striving for enhancements.
• Ensure regulatory compliance and understanding.

Manufacturing Support:

• Support first-time manufacturing operations and troubleshoot scale-up issues.
• Maintain safety and hygiene standards.
• Comply with COSHH and risk assessments.

Training:

• Manage staff utilization, training, and development.

Critical Tasks:

• Manage project scope and milestones.
• Ensure accuracy of raw data and analytical interpretations.
• Interface with clients and handle new project inquiries.
• Provide technical support for transferred or developed processes.

Key Result Areas & Measures:

• Deliver projects on time, within budget, and to quality standards.
• Engage in client interactions and new project proposals.

Critical Skills:

• Protein modification, conjugation chemistry, ADC purification.
• Process robustness, optimization, and product characterization.
• Analytical characterization of bioconjugates.
• Technical expertise in bioconjugation programs.
• Data interpretation, presentation, and reporting.
• Strong collaboration skills internally and externally.
• Proven track record in planning and delivering development programs.