Principal Scientist - Non-clinical PKPD

ZipRecruiter; Slough; On-site; GBP 45,000 - 70,000; Full time

Job summary

A successful biopharmaceutical company is seeking an experienced scientist to lead non-clinical PKPD strategy in Slough. Responsibilities include designing studies, analyzing data using Phoenix WinNonLin, and ensuring compliance in documentation. Candidates should have a PhD/MSc/BSc in a relevant field and over 5 years of experience in PKPD analysis. This role allows for hybrid working, with a requirement to be onsite at least two days a week.

Qualifications

• 5+ years’ PKPD analysis experience in pharma/CRO.
• Strong understanding of pharmacology and drug action.
• Proven track record in regulatory-standard study design and reporting.

Responsibilities

• Lead design and execution of non-clinical PKPD studies.
• Analyse data and communicate results effectively.
• Collaborate with internal teams and CROs to deliver high-quality data.

Skills

PKPD analysis

Data analysis

Communication skills

Project management

Education

PhD/MSc/BSc in relevant discipline

Tools

Phoenix WinNonLin

Berkeley Madonna

R

Job description

Job Description

This is an opportunity to join a successful biopharmaceutical company, delivering novel solutions to a range of disease areas. Using integrated PKPD, modelling, and DMPK approaches you will drive smarter drug development — from target ID to first in human clinical trials.

We’re looking for an experienced scientist to lead non-clinical PKPD strategy, working across study design, data analysis, and regulatory submissions to help bring new therapies to patients.

Responsibilities:

• Lead design and execution of non-clinical PKPD and GLP toxicokinetics studies
• Analyse data using Phoenix WinNonLin, Berkeley Madonna and R
• Produce clear reports and regulatory-standard documentation
• Collaborate with internal teams and CROs to deliver high-quality, compliant data
• Communicate results effectively to scientific and project stakeholders

Ideal Profile:

• PhD/MSc/BSc in relevant discipline, 5+ years’ PKPD analysis experience in pharma/CRO
• Strong understanding of pharmacology and drug action
• Proven track record in regulatory-standard study design and reporting inc. strong experience with WinNonLin
• Excellent communication skills and ability to work in a matrix environment
• Organised, proactive, and able to manage multiple projects

Day to day responsibilities can be carried out either onsite or at home with a requirement for the job holder to be onsite at least 2 days/week.

The role is offered on an initial 12 month contract basis with realistic potential for extension.

Apply to VRS today!

Keywords: PK, PD, pharmacokinetics, pharmacodynamics, pharmacology, DMPK, metabolism, pharmaceutical, toxicology, WinNonLin, Berkshire, Reading, Slough, London, VRS9114SE