PRINCIPAL SCIENTIST - CLINICAL PHARMACOLOGY

Maxion Therapeutics; Pampisford; On-site; GBP 50,000 - 80,000; Full time

Job summary

Maxion Therapeutics seeks a Principal Scientist in Clinical Pharmacology to manage clinical activities for their lead program, MAX001. Ideal candidates should have a robust background in biologics development and possess strong project management and communication skills. This permanent position offers a comprehensive benefits package, significant career growth opportunities, and a dynamic working environment near Cambridge.

Benefits

Generous pension contribution

Private Life and Medical Insurance

Cycle to Work Scheme

Participation in company Share Option Scheme

Qualifications

• Degree in Life Sciences, Chemistry or equivalent.
• Strong experience in pharmaceutical industry and development of biologics.
• Expertise in Clinical Pharmacology, including PK and immunogenicity.

Responsibilities

• Manage Clinical Pharmacology aspects for MAX001.
• Implement Clinical Pharmacology strategies and present to teams.
• Coordinate all pharmacokinetic and immunogenicity studies.

Skills

Project Management

Communication

Organizational skills

Problem-solving

Education

Degree in Life Sciences

Pharmaceutical Sciences

Job description

PRINCIPAL SCIENTIST - CLINICAL PHARMACOLOGY

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PRINCIPAL SCIENTIST - CLINICAL PHARMACOLOGY

Pampisford - Unity Campus UK

About Maxion

Maxion Therapeutics is a biotechnology company developing antibody-based drugs for previously untreatable ion channel- and G protein-coupled receptor (GPCR)-driven diseases, including autoimmune conditions, chronic pain, and cardiovascular disease.

The Company is developing a pipeline of potentially first- and best-in-class therapeutics using its proprietary KnotBody technology to generate potent, selective, and long-acting therapeutics by combining naturally occurring mini-proteins (‘knottins’) with antibodies using state-of-the-art phage and mammalian display technologies.

Maxion was founded in 2020 by highly respected biotech entrepreneurs and scientists Dr John McCafferty, CTO and Dr Aneesh Karatt-Vellatt, CSO. Dr McCafferty previously co-invented antibody phage display, which was the subject of the 2018 Nobel Prize in Chemistry awarded to his co-inventor Sir Gregory Winter.Maxion’s portfolio and growth is being advanced by a team of highly experienced leaders in the discovery and development of antibody-based drugs. The Company is based near Cambridge, UK and is backed by international blue-chip investors. For more information, please visit:

https://www.maxiontherapeutics.com/.

About the Role

We are seeking a highly organised and proactive Clinical Pharmacologist to oversee and manage all clinical pharmacology activities for our lead programme, MAX001, currently in IND-enabling development. Reporting directly to the Chief Development Officer (CDO), the successful candidate will assume full responsibility for managing and coordinating all Pharmacokinetic, Immunogenicity and Bioanalytical studies.

The ideal candidate will have a strong background in non-clinical and early clinical development of biologics, excellent communication skills, and a collaborative approach to working with internal and external stake holders.

Key responsibilities

• Manage all Clinical Pharmacology aspects for MAX001 during pre-clinical and clinical development
• Implement project specific Clinical Pharmacology strategies and present these to internal teams
• Interact with internal bioanalytical team members as well as CROs for the development, transfer and validation of PK, immunogenicity and selected pharmacodynamic assays
• Closely interact with other functions within the Research and Development area to optimize non-clinical and clinical development concepts
• Coordinate and prepare Clinical Pharmacology related sections in all submission relevant documents such as IB, study protocols, study reports, IND dossier documents as well as publications

Candidate Profile

• Degree in Life Sciences, Chemistry, Pharmaceutical Sciences or equivalent relevant experience.
• Strong Pharmaceutical industry experience preferentially with a background in the development of new biologic entities (NBEs)
• Expertise in Clinical Pharmacology comprising PK, PK/PD, immunogenicity and ideally DER data analysis and application of model-informed drug development
• Strong project management, organisational, and communication skills.
• Ability to effectively manage priorities, problem-solve proactively, and adapt to rapidly evolving project demands.
• Actively contributing to a vibrant and innovative working environment where improvements and new ideas are adopted and freely shared among the teams.
• Desire and ability to work in a fast-paced, quickly changing environment, showing agility/flexibility to meet deadlines and goals with a can-do attitude.

What can we offer you?

• A comprehensive benefits package including generous pension contribution, Private Life and Medical Insurance, Cycle to Work Scheme, participation in the company Share Option Scheme, and more.
• Significant opportunities for career progression within a dynamic company.
• Located in a state-of-the art Science Park with easy access to Cambridge by car, train and bus, and offering on-site gym, cafe, and a vibrant social community.
• Working alongside an innovative team of scientists, including the founders, who are Key Opinion Leaders in the field.
• A supportive work environment with a key focus on fostering collaborative working environment within a friendly team.

To apply for this position, click on the link to upload your CV and covering letter outlining your suitability for this role, including your salary expectations.

We cannot accept direct messages via linked in with CV's.

This is a permanent position.

Agencies: We are recruiting this role directly with our in-house talent team, so do not need support from agencies. We also have our own preferred suppliers list which is not being reviewed for additions in the next 12 months.

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Full-time

Job function

• Job function

  Science and Research

• Industries

  Biotechnology, Biotechnology Research, and Pharmaceutical Manufacturing

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