Principal Scientist - Biomarkers Discovery

JR United Kingdom; London; On-site; GBP 50,000 - 80,000; Full time

Job summary

A leading scientific research organization is seeking a Principal Scientist to join its founding team. This role involves leading laboratory work on biomarker assays, managing a small team, and contributing to the scientific strategy. The successful candidate will have significant influence on research direction and the opportunity for accelerated career growth in a dynamic environment.

Benefits

Accelerated career growth

Opportunity to impact cutting-edge research

Dynamic, self-driven long-term progression

Qualifications

• Experience managing laboratory operations with compliance responsibilities.
• Strong understanding of biomarker discovery and validation.
• Hands-on experience in bioanalytical assay development.

Responsibilities

• Lead the scientific direction of laboratories for biomarker identification.
• Develop and validate advanced 'Omics assays.
• Supervise a small scientific team ensuring quality and compliance.

Skills

Leadership

Project Management

Client Interaction

Technical Expertise

Education

MSc or PhD in molecular biology, cell biology, biochemistry

Tools

LIMS

Data Management Systems

Job description

Summary:

Emles BioVentures is a cutting-edge scientific research organization committed to accelerating and supporting innovative approaches that have the potential to significantly improve human HealthSpan and longevity. Our mission is to push the boundaries of science to uncover groundbreaking discoveries that can transform how we age and enhance our overall well-being. At Emles BioVentures, we believe that extending the healthy years of life is not just a possibility but an imminent reality.

We are launching our own laboratories to accelerate our research programs. We seek a highly skilled and motivated Principal Scientist to be part of the founding team. The successful candidate will influence the scientific strategy of the company, utilizing expertise, innovation, and creative thinking to maximize the impact of our science. The role involves leading work from the bench for external client programs and internal R&D, with additional responsibilities for laboratory management, supported by the leadership team, including full commercial, regulatory, and QMS support.

The laboratory's purpose is to develop novel biomarker assays to enhance health monitoring with potential for commercialization and scientific breakthroughs. It will also run ‘omics assays as a service for academic, biotech, and biopharmaceutical clients, collaborating on research and commercialization programs. The role requires designing research programs to solve complex problems and driving internal research to support further commercialization efforts.

Key Responsibilities:

• Lead the scientific direction of the laboratories for biomarker identification and commercialization.
• Develop, validate, and operate advanced 'Omics assays.
• Contribute to the company's scientific strategy alongside the leadership team.
• Serve as a key contact for clients and internal research teams.
• Assist in setting up new laboratory and office facilities.
• Supervise a small scientific team, ensuring quality, compliance, and timely delivery.
• Support assay development and troubleshooting within the scientific team.
• Ensure operational efficiency of the laboratories, including equipment maintenance, supplies, and operational systems.

Qualifications:

• MSc or PhD in molecular biology, cell biology, biochemistry, or related fields.
• Experience managing laboratory operations with compliance and service delivery responsibilities.
• Hands-on experience in bioanalytical assay development (e.g., ELISA, NGS, qPCR).
• Experience in proteomic assay design, execution, and troubleshooting.
• Strong understanding of biomarker discovery and validation for clinical or translational research.
• Knowledge of regulatory frameworks beyond GCP/GLP (e.g., ISO 15189, CAP, HTA).
• Experience establishing new laboratories is advantageous but not essential.
• Proven leadership and mentorship abilities, including performance management.
• Familiarity with LIMS and data management systems.
• Experience in client interaction, project scoping, and delivery.
• Strong project management skills in a fast-paced environment.
• Track record of publications, patents, or grant contributions.
• Experience managing vendor relationships, negotiations, and budgets.

Why Join Us?

You will join a newly established laboratory with the opportunity to impact cutting-edge research leading to breakthroughs in this rapidly evolving field. The role offers significant growth potential and long-term career progression supported by a dedicated internal expertise platform.

What does this mean?

• Accelerated career growth
• Apply your technical and personal talents
• Make a genuine impact on a business at the forefront of science
• Work in a truly innovative environment
• Modern, deliverable-focused work approach
• Dynamic, self-driven long-term progression