Principal Scientist - Bioassay Development

Hyper Recruitment Solutions Ltd; London; On-site; GBP 55,000 - 65,000; Full time

Job summary

A leading company in gene therapy is seeking a Principal Scientist – Bioassay Development for a 12-month contract in London. This key role involves developing potency assays for gene therapy products, collaborating with clinical teams, and providing regulatory support. Candidates should have a relevant biological sciences degree and extensive experience in the industry, particularly with AAV and assay development.

Qualifications

• Extensive industry experience in bioassay development and product characterization.
• Practical experience with AAV cell-based assay development, including infectivity and functional assays.

Responsibilities

• Design and develop in vitro potency assays suitable for clinical trials.
• Lead the development and troubleshooting of bioassays while ensuring high laboratory standards.
• Collaborate with research teams for successful project delivery.

Skills

Bioassay Development

In vitro Assay Design

Collaboration

Regulatory Knowledge

Analytical Development

Cell Culture

Education

Relevant degree in biological sciences

Job description

Principal Scientist - Bioassay Development

14621Permanent £55,000 - £65,000 Site Based London, Greater London, United Kingdom Updated on: 04-06-2025

ROLE OVERVIEW

A leading company in the gene therapy sector is seeking a Principal Scientist – Bioassay Development for a 12-month contract based in London, UK. This role offers the chance to work with a pioneering organisation focused on advancing gene therapies for chronic renal diseases.

As the Principal Scientist – Bioassay Development, you will play a critical role in the development and application of in vitro potency assays for gene therapy products, particularly those involving AAV.

KEY DUTIES AND RESPONSIBILITIES:
Your duties as the Principal Scientist – Bioassay Development will be varied however the key duties and responsibilities are as follows:

1. Design, develop, and qualify in vitro potency assays suitable for product release for human clinical trials.
2. Lead the development, execution, training, and troubleshooting of bioassays, ensuring high standards of laboratory practices.
3. Collaborate closely with research, clinical teams, and external collaborators to ensure successful project delivery.
4. Support the Regulatory team by providing technical expertise for regulatory submissions.

ROLE REQUIREMENTS:
To be successful in your application to this exciting role as the Principal Scientist – Bioassay Development we are looking to identify the following on your profile and past history:

1. Relevant degree in biological sciences.
2. Extensive industry experience in bioassay development and product characterisation, particularly for gene therapy products.
3. A working knowledge and practical experience with AAV cell-based assay development, including infectivity, relative infectivity, expression, and functional assays.

Key Words: Principal Scientist / Bioassay Development / Gene Therapy / AAV / Potency Assays / Biotechnology / Analytical Development / Cell Culture / GMP / Regulatory Submissions / London / Bioanalytical

Hyper Recruitment Solutions Ltd (HRS) is an Equal Opportunities employer. We welcome applications from anyone who meets the role requirements. HRS exclusively supports the Life Science sectors, combining recruitment expertise with scientific knowledge to help you advance your career.

Hyper Recruitment Solutions Ltd (HRS) is an Equal Opportunities employer. We welcome applications from anyone who meets the role requirements. HRS exclusively supports the STEM sectors, combining recruitment expertise with scientific knowledge to help you advance your career.

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