Principal Scientist - Bioassay Development

Hyper Recruitment Solutions Ltd; Greater London; On-site; GBP 55,000 - 65,000; Full time

Job summary

A leading company in gene therapy is seeking a Principal Scientist – Bioassay Development for a 12-month contract in London. You will design in vitro potency assays for gene therapy products, ensuring high standards in laboratory practices. Ideal candidates will have a relevant biological sciences degree and extensive experience in bioassay development, particularly involving AAV cell-based assays. This role offers an exciting opportunity to work within a pioneering organisation focused on advancing gene therapies.

Qualifications

• Relevant degree in biological sciences.
• Extensive industry experience in bioassay development.
• Practical experience with AAV cell-based assay development.

Responsibilities

• Design, develop, and qualify potency assays.
• Lead development and troubleshooting of bioassays.
• Collaborate with teams for project delivery.
• Provide technical expertise for regulatory submissions.

Skills

Bioassay development

AAV cell-based assay development

Analytical development

GMP compliance

Cell culture

Education

Degree in biological sciences

Job description

Principal Scientist - Bioassay Development

14621Permanent £55,000 - £65,000 Site Based Greater London, United Kingdom Updated on: 24-07-2025

ROLE OVERVIEW

A leading company in the gene therapy sector is seeking a Principal Scientist – Bioassay Development for a 12-month contract based in London, UK. This role offers the chance to work with a pioneering organisation focused on advancing gene therapies for chronic renal diseases.

As the Principal Scientist – Bioassay Development, you will play a critical role in the development and application of in vitro potency assays for gene therapy products, particularly those involving AAV.

KEY DUTIES AND RESPONSIBILITIES:
Your duties as the Principal Scientist – Bioassay Development will be varied however the key duties and responsibilities are as follows:

1. Design, develop, and qualify in vitro potency assays suitable for product release for human clinical trials.
2. Lead the development, execution, training, and troubleshooting of bioassays, ensuring high standards of laboratory practices.
3. Collaborate closely with research, clinical teams, and external collaborators to ensure successful project delivery.
4. Support the Regulatory team by providing technical expertise for regulatory submissions.

ROLE REQUIREMENTS:
To be successful in your application to this exciting role as the Principal Scientist – Bioassay Development we are looking to identify the following on your profile and past history:

1. Relevant degree in biological sciences.
2. Extensive industry experience in bioassay development and product characterisation, particularly for gene therapy products.
3. A working knowledge and practical experience with AAV cell-based assay development, including infectivity, relative infectivity, expression, and functional assays.

Key Words: Principal Scientist / Bioassay Development / Gene Therapy / AAV / Potency Assays / Biotechnology / Analytical Development / Cell Culture / GMP / Regulatory Submissions / London / Bioanalytical

Hyper Recruitment Solutions Ltd (HRS) is an Equal Opportunities employer. We welcome applications from anyone who meets the role requirements. HRS exclusively supports the Life Science sectors, combining recruitment expertise with scientific knowledge to help you advance your career.

Hyper Recruitment Solutions Ltd (HRS) is an Equal Opportunities employer. We welcome applications from anyone who meets the role requirements. HRS exclusively supports the STEM sectors, combining recruitment expertise with scientific knowledge to help you advance your career.

Biological Sciences, Featured Job, Science

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