Principal Research Scientist I-Genetic Characterization (On site, Worcester, MA)

ZipRecruiter; Worcester; On-site; GBP 70,000 - 100,000; Full time

Job summary

A leading company in innovative medicines seeks a Principal Scientist to lead the Molecular Biology team. This role involves developing strategies for biological assets, overseeing cell line development, and applying cutting-edge technologies. The ideal candidate will have extensive experience in molecular biology and a proven ability to innovate and solve complex problems. Join a dynamic environment where you can make a significant impact on drug development.

Qualifications

• 14+ years experience with a BS, 12+ with an MS, or 6+ with a PhD in relevant fields.
• Proven track record in drug candidate development and molecular biology techniques.

Responsibilities

• Lead the Molecular Biology team and manage multiple projects.
• Develop and execute strategies for biological asset transition.
• Identify and implement advanced technologies for pipeline programs.

Skills

Collaboration

Problem Solving

Creative Thinking

Education

PhD in Biology

MS in Biology

BS in Biology

Tools

NGS

Omics

AI/ML

High-throughput Automation

Job description

Job Description

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn, and TikTok.

Job Description

Operation PDST Biological Development and Launch at AbbVie is seeking a highly motivated Principal Scientist with a strong understanding of early and late-stage biological pipeline cell line development and genetic characterization to lead the Molecular Biology team at the AbbVie Bioresearch Center (ABC). The ABC site, based in Worcester, MA, offers a unique setting where biologics drug discovery, development, and manufacturing coexist in one location. The leader will be responsible for asset transition from discovery into development, vector construct development, cell line development, cell bank genetic characterization and qualification, as well as modernizing traditional molecular biology methods through innovation and developing next-generation genetic characterization platform processes. Experience with cutting-edge technologies such as NGS, Omics, AI/ML, high-throughput automation, and digitalization for process optimization are also valued.

Responsibilities:

1. Develop and execute discipline strategy aligned with functional goals and scientific objectives, ensuring successful transition of AbbVie biological assets from discovery to development.
2. Guide the development and genetic characterization of cell lines and cell banks across all pipeline stages.
3. Identify and implement advanced technologies to support accelerated biological pipeline programs.
4. Provide strategic, operational, and scientific guidance to the molecular biology team.
5. Conduct laboratory research independently, troubleshooting experimental designs and equipment as needed.
6. Apply creative thinking to solve complex problems and promote new technologies, effectively communicating ideas to diverse audiences.
7. Manage multiple projects across therapeutic areas within a dynamic, fast-paced environment.
8. Present scientific concepts and results to scientific and non-scientific stakeholders, maximizing impact and value.
9. Advance scientific expertise within the function, mentoring colleagues, sharing knowledge, and assessing emerging business challenges to achieve goals.

Qualifications:

• BS with 14+ years, MS with 12+ years, or PhD with 6+ years of experience in Biology, Molecular and Cellular Biology, or related fields.
• Strong interpersonal skills and ability to collaborate across diverse groups.
• Broad experience in cell line development across various cell types, with a proven track record in drug candidate development.
• Expertise in molecular biology techniques, including plasmid construction and genetic characterization.
• Innovative with a history of developing new methods or workflows.
• Strong attention to detail in organizational, documentation, and communication skills, fostering effective collaboration.

Additional Information

This section provides information on compensation, benefits, and equal opportunity employment policies, emphasizing the company's commitment to diversity and inclusion. Specific pay ranges are provided based on location and experience, with details on benefits and incentive programs. Applicants seeking accommodations can find more information via provided links.