Principal Health Economics Modeller

Scientis Search Ltd; Cardiff; On-site; GBP 90,000 - 130,000; Full time

Job summary

Scientis Search Ltd. seeks a Principal Health Economics Modeller with a strong mathematical background to lead bespoke health economic modelling across pharmaceuticals, diagnostics, devices and healthcare delivery.

You will provide scientific and technical leadership, translate complex questions into robust models, manage a small team, and maintain senior client relationships while advancing the company's modelling capability.

Qualifications

• Degree or postgraduate qualification in mathematics, applied mathematics, health economics, statistics, or a closely related quantitative discipline.
• Significant experience developing mathematical and health economic models.
• Experience designing and developing complex models from conceptualisation to implementation.
• Analytical capability and technical creativity to develop bespoke modelling approaches.
• Strong programming and computational modelling skills with experience of modelling environments and tools.
• Experience leading technical projects, managing client relationships, and communicating findings to senior stakeholders.
• Ability to lead, mentor and develop other modellers, providing technical guidance and project oversight.
• Strong commercial awareness and ability to contribute to proposals and client relationships.

Responsibilities

• Lead the conceptualisation, design, development, and validation of complex mathematical and health economic models, including bespoke de novo models, cost-effectiveness, and budget impact models.
• Apply advanced mathematical and analytical techniques to investigate complex clinical, economic, and healthcare questions.
• Develop innovative modelling approaches where established methodologies are insufficient.
• Provide scientific and technical direction across multiple projects, ensuring rigour and high-quality, fit-for-purpose models.
• Work directly with clients and senior stakeholders to define project objectives and communicate technical findings.
• Lead and develop a small team of modellers, mentoring and overseeing project delivery.
• Take responsibility for project planning, technical reporting, model documentation, and presenting findings to clients.
• Contribute to proposals, project scoping, and development of client relationships.

Skills

Mathematical modelling

Health economics

Leadership

Client engagement

Programming

Education

Mathematics / quantitative discipline

Job description

We are seeking a highly accomplished Principal Health Economics Modeller with a strong mathematical background and the technical creativity to develop sophisticated models that address complex healthcare challenges.

Working within a successful and growing specialist consultancy, you will lead the development of scientifically rigorous, bespoke mathematical models that support decision-making across pharmaceuticals, diagnostics, medical devices, and healthcare delivery.

This is a technically demanding position requiring more than the application of established health economic modelling methodologies. You will be responsible for developing innovative modelling approaches, including bespoke de novo models, translating complex scientific and clinical questions into robust mathematical frameworks and delivering solutions that are transparent, intuitive, and fit for purpose.

Alongside your technical contribution, you will provide leadership to a small but growing team of modellers, manage senior client relationships, and play an important role in the continued development of the company's Modelling and Analytics capability.

The Company

Our client is a highly successful, independent healthcare consultancy with an established reputation for scientific excellence and the development of sophisticated analytical solutions.

Founded by a mathematician with a PhD in Mathematics, specialising in health economics modelling, the company has built a modelling and analytics capability that extends well beyond conventional health economic modelling. Its expertise encompasses a broad range of modelling methodologies, with particular strength in developing bespoke models to investigate complex clinical, economic, and healthcare questions.

The company combines the scientific depth of a specialist research environment with the pace and variety of a successful consultancy. Its collaborative culture encourages intellectual curiosity, scientific creativity, and the development of innovative approaches to challenging problems.

With an established client base and continued growth, the company offers the opportunity to undertake technically demanding work with meaningful real-world impact, within a supportive environment that values its people and recognises the importance of work-life balance.

The Role

As Principal Health Economics Modeller, you will provide scientific and technical leadership across a portfolio of complex modelling projects, working with clients to understand their objectives and develop appropriate mathematical and analytical solutions.

You will have responsibility for the technical direction, quality, and delivery of projects, while remaining closely involved in the conceptualisation and development of models.

The role combines advanced mathematical modelling with project leadership, client engagement and the management and development of a small team.

Key responsibilities include:

• Leading the conceptualisation, design, development, and validation of complex mathematical and health economic models, including bespoke de novo models, cost-effectiveness, and budget impact models.
• Applying advanced mathematical and analytical techniques to investigate complex clinical, economic, and healthcare questions.
• Developing innovative modelling approaches where established methodologies are insufficient to address the underlying problem.
• Providing scientific and technical direction across multiple projects, ensuring methodological rigour, appropriate validation, and the delivery of high-quality, fit-for-purpose models.
• Working directly with clients and senior stakeholders to define project objectives, advise on modelling strategies, challenge assumptions, and communicate technical findings.
• Leading and developing a small team of modellers, providing technical guidance, mentoring, and oversight of project delivery.
• Taking responsibility for project planning, technical reporting, model documentation, and the presentation of findings to clients.
• Contributing to proposals, project scoping, and the development of existing and new client relationships.
• Supporting the continued development of the company's modelling methodologies, technical capabilities and wider Modelling and Analytics team.

About You

We are looking for a mathematically accomplished and scientifically rigorous individual who enjoys solving complex problems and has the experience to lead both technical projects and people.

You will bring:

• A degree or postgraduate qualification in mathematics, applied mathematics, health economics, statistics, or a closely related quantitative discipline.
• Significant experience in the development of mathematical and health economic models, with a strong understanding of the underlying mathematical principles.
• Experience designing and developing complex models, from initial conceptualisation and mathematical formulation through to implementation, validation, and interpretation.
• The analytical capability and technical creativity to develop bespoke modelling approaches rather than relying exclusively on established methodologies.
• Strong programming and computational modelling skills, with experience of relevant modelling environments and tools.
• Experience leading technical projects, managing client relationships, and communicating complex analytical findings to senior stakeholders.
• The ability to lead, mentor and develop other modellers, providing both technical guidance and effective project oversight.
• Strong commercial awareness and the ability to contribute to project proposals, scoping, and the development of client relationships.

Experience within health economics, HEOR or healthcare consultancy would be particularly relevant, alongside a strong mathematical and analytical foundation.

You will be someone who enjoys the intellectual challenge of mathematical modelling, values scientific rigour and wants to apply their expertise to problems with meaningful healthcare impact.

The Opportunity

This is an opportunity to combine advanced mathematical modelling with genuine technical influence and leadership responsibility.

You will join a successful, growing consultancy where scientific expertise is central to the business, with the freedom to develop new modelling approaches, contribute ideas and influence the future direction of the team.

The company offers a collaborative and supportive working environment, a healthy approach to work-life balance and the opportunity to build a long-term career while contributing to important decisions in healthcare.