Principal Biostatistician

ICON plc; Swansea; On-site; GBP 50,000 - 90,000; Full time

Job summary

An established industry player is seeking a Principal Biostatistician to lead the design and analysis of clinical trials in oncology. This role involves overseeing statistical activities, approving research proposals, and providing statistical consulting for clients. The successful candidate will have extensive experience in biostatistics and oncology, with a strong emphasis on leadership and communication skills. Join a forward-thinking organization dedicated to innovation and excellence, where your contributions will help shape the future of clinical development and improve patient outcomes globally. If you are passionate about making a difference in healthcare, this opportunity is perfect for you.

Benefits

Various annual leave entitlements

Health insurance offerings

Competitive retirement planning

Global Employee Assistance Programme

Life assurance

Flexible optional benefits

Qualifications

• 9+ years of biostatistical experience with a Master's or 7+ years with a Ph.D.
• 3+ years of experience in oncology leading phase 1-3 clinical trials.

Responsibilities

• Lead biostatistician for program-level studies and submissions.
• Oversee statistical activities supporting client interactions and regulatory agencies.

Skills

Biostatistics

Statistical analysis

Oncology expertise

Leadership skills

Communication skills

Education

Master’s degree in Biostatistics

Ph.D. in Statistics

Tools

Bayesian methods

iRECIST

Lugano criteria

Job description

Principal Biostatistician- EMEA Oncology

ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.

We are currently seeking a Principal Biostatistician to join our diverse and dynamic team. In this role, you will be integral to the design and analysis of clinical trials, interpretation of complex medical data, and the advancement of groundbreaking treatments and therapies.

As a member of our Biotech Full Service division you will be supporting small and medium-sized biotech clients. Within the Oncology account group we are looking for Biostatisticians to lead phase 1-3 Oncology clinical trials.

What You Will Be Doing:

• Lead biostatistician for program-level studies, submissions, or individual studies ranging from simple to complex.
• Oversee statistical activities that support ICON’s interactions with clients and regulatory agencies.
• Review and approve statistical methods sections of study protocols, statistical analysis plans, and contribute to the statistical input in reports.
• Prepare and approve research proposals and budgets, providing statistical consulting and conducting statistical analyses for clients.
• Participate in bid defense meetings and deliver presentations at marketing meetings with prospective clients.

Your Profile:

• Master’s degree or Ph.D. in Biostatistics, Statistics, or a related field, with at least 9 years of biostatistical experience for those with a Master’s degree, or 7 years for those with a Ph.D.
• A minimum of 3 years’ experience in oncology, with expertise in leading phase 1-3 clinical trials.
• In-depth knowledge of RECIST.
• Experience with iRECIST and Lugano criteria is a plus.
• Knowledge of Bayesian methods is an added advantage.
• Advanced skills in planning, supervising, implementing, and monitoring statistical processes across multiple clinical studies.
• Strong written and oral communication skills, with proven leadership capabilities.

What ICON can offer you:

Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our benefits examples include:

• Various annual leave entitlements
• A range of health insurance offerings to suit you and your family’s needs.
• Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
• Global Employee Assistance Programme, offering 24-hour access to a global network of over 80,000 independent specialised professionals who are there to support you and your family’s well-being.
• Life assurance
• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidised travel passes, health assessments, among others.

At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here.

Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles.