Postdoctoral Research Scientist - Epitranscriptomics

University-of-Oxford; Oxford; On-site; GBP 39,000 - 48,000; Full time

Job summary

University of Oxford invites applications for two Postdoctoral Research Scientists in Epitranscriptomics within Dr. Chunxiao Song’s group at the Target Discovery Institute, Nuffield Department of Medicine, Oxford.

The role focuses on pseudouridine biology, PUS enzymes, and cfRNA diagnostics for cancer, with emphasis on advancing RNA modification mapping technologies. Successful candidates will lead projects, design experiments, analyze data, contribute to funding proposals and publications, and

Qualifications

• PhD or near completion in molecular biology or related field.
• Strong practical skills in molecular biology, biochemistry, or cell biology.
• Experience with RNA biology or epitranscriptomics.
• Publications in relevant fields and excellent communication.

Responsibilities

• Manage and lead research projects.
• Develop and adapt experimental techniques.
• Analyze scientific data and report findings.
• Contribute to proposals and publish manuscripts.
• Collaborate with partner institutions.

Skills

Molecular biology

Biochemistry

Cell biology

Epitranscriptomics

RNA sequencing

Scientific communication

Education

PhD in Molecular Biology

Tools

Next-generation sequencing

Bioinformatic data analysis

NGS analysis tools

Job description

Postdoctoral Research Scientist - Epitranscriptomics

Target Discovery Institute, NDM Research Building, Old Road Campus, Headington, Oxford, OX3 7FZ

We are seeking to appoint two Postdoctoral Research Scientists in Epitranscriptomics to join Dr Chunxiao Song’s research group at the Target Discovery Institute, Nuffield Department of Medicine. You will contribute to research investigating the role of pseudouridine and pseudouridine synthases (PUS) in cancer, alongside exploring the clinical applications of pseudouridine in circulating cell-free RNA for cancer diagnostics. The group develops cutting-edge technologies for high-resolution mapping of DNA and RNA modifications, translating discoveries in epigenetics and epitranscriptomics into diagnostic and therapeutic opportunities.

You will be responsible for managing and leading research projects, developing and adapting experimental techniques, testing hypotheses and analysing scientific data. The role includes contributing to research development and funding proposals, preparing scientific reports and journal articles, presenting research findings and providing specialist advice on experimental protocols and techniques. You will also collaborate with researchers and partner institutions, contributing to the development of innovative approaches in RNA biology and epitranscriptomics.

It is essential that you hold, or are close to completing, a relevant PhD/DPhil in Molecular Biology, Biochemistry, Cell Biology, Chemistry or a related scientific discipline, together with relevant research experience. You should have strong practical skills in molecular biology, biochemistry or cell biology, specialist knowledge of RNA biology or epitranscriptomics, and the ability to independently manage and lead research projects. Excellent communication skills and experience contributing to scientific publications are also required. Experience with next-generation sequencing, bioinformatic data analysis, liquid biopsy or cell-free RNA sequencing, supervising researchers or students, and first-author publications in a relevant field would be advantageous.

This position is offered full time on a fixed term contract for 24 months and is funded by Cancer Research UK.

Only applications received before 12 midday on 11 November 2026 will be considered.

Salary (£) : Research Grade 7: Salary in range £39,424 - £47,779 per annum (pro rata). This is inclusive of a pensionable Oxford University Weighting of £1,730 per year (pro rata).