Postdoctoral Research Fellow in Gene Therapy

Royal Veterinary College; Camden Town; On-site; GBP 41,000 - 52,000; Full time

Benefits offered by this job

Competitive pension

30 days annual leave

On site café & restaurant

Fitness and Wellbeing Centre on site

Cycle to work scheme

Family friendly policies

Job summary

Royal Veterinary College is inviting applications for a Postdoctoral Research Fellow in Gene Therapy to work in the Department of Comparative Biomedical Sciences, Camden Town, London. The project focuses on polymer-coated AAV vectors for Duchenne muscular dystrophy, with strong molecular biology requirements and collaboration across the lab.

The role requires experience with Western blotting, immunocytochemistry, qPCR, and aseptic culture; in vivo work is desirable.

Qualifications

• Expertise in western blotting, immunocytochemistry, quantitative PCR and aseptic cell culture is essential.
• Experience with Adeno-associated virus (AAV) vector production and use in vitro and in vivo is essential; in vivo experience desirable.
• Strong molecular biology skills and interest in neuromuscular conditions; ability to communicate and work independently and collaboratively.

Responsibilities

• Conduct research on polymer-coated AAV vectors for gene replacement therapy in Duchenne muscular dystrophy.
• Perform experiments including western blot, immunocytochemistry and quantitative PCR; maintain aseptic cell culture.
• Collaborate with laboratory team and present findings to stakeholders; participate in interview presentations if shortlisted.

Skills

Molecular biology

Western blotting

Immunocytochemistry

Quantitative PCR

Aseptic cell culture

AAV vector production

In vivo work

Tools

AAV vectors

Job description

Postdoctoral Research Fellow in Gene Therapy (CBS-0266-26)

Royal Veterinary College

View all jobs

• Camden Town, North West London
• £41,339-52,499 per year
• Permanent
• Full-time

10 hours ago

Applications are invited for a position of postdoctoral scientist to be spent at the Department of Comparative Biomedical Sciences at the Royal Veterinary College.

The focus of the project, funded by the U.S. Department of Defense, is to test novel polymer-coated adeno-associated viral vectors for gene replacement therapy in Duchenne muscular dystrophy. Given the nature of the project, we are seeking to appoint a highly motivated and enthusiastic scientist with excellent molecular biology skills and strong interest in neuromuscular conditions.

Expertise in western blotting, immunocytochemistry, quantitative PCR, and aseptic cell culture are essential. Previous experience in Adeno-associated virus (AAV) vector production and use in vitro and in vivo is essential. In vivo expertise is desirable. Training will be provided for any unfamiliar techniques. You are expected to be a good communicator, able to work both independently and collaboratively with other members of the laboratory.

Candidates invited to the interview will be asked to prepare a short (10 minutes) presentation of their recent research.

The position is funded for 14 months.

We offer a generous reward package and benefits including:

• Competitive and attractive pension package
• Generous 30 days annual leave (plus bank holidays and concessionary days) pro-rata
• On site café and restaurant
• Free membership to the Fitness and Wellbeing Centre located on site
• Cycle to work scheme
• A range of family friendly policies, including adoption, maternity and paternity pay and leave

For an informal discussion about the post, please contact Dr Alberto Malerba.

Further Details

We promote equality of opportunity and diversity within the workplace and welcome applications from all sections of the community.

We reserve the right to close this vacancy early if we receive sufficient applications for the role. We therefore encourage you to submit your application as soon as possible.