Postdoctoral Research Associate in Radiopharmaceutical Development

King's College London; London; On-site; GBP 40,000 - 58,000; Full time

Job summary

A leading university is seeking a developmental scientist focused on radiopharmaceuticals to join their multidisciplinary team. This full-time role involves significant contributions to drug development and clinical applications, ideal for candidates with relevant advanced degrees and a passion for translational research.

Qualifications

• PhD level qualified in chemical or biomedical science.
• Advanced knowledge in small molecule therapeutic drug development.
• Expertise in efficacy assay development.

Responsibilities

• Develop novel radiopharmaceuticals.
• Provide expertise in a multidisciplinary team.
• Optimise in vitro and in vivo efficacy assays.

Skills

Inter-personal skills

Study/experimental design

Data analysis

Therapeutic drug development

Education

PhD in chemical or biomedical science

Tools

In vitro and in vivo models

Translational criteria

Job description

About Us

The Faculty of Life Sciences & Medicine is one of the largest and most successful centres for research and education in the UK. The Faculty was created as a result of the merger of elements of the School of Biomedical Sciences with the School of Medicine. The merger brings together basic, translational and clinical scientists to provide new cross-School research collaborations while optimising the deployment of teaching expertise across the Faculty. The Faculty has unparalleled expertise in basic, translational and clinical research in: analytical and forensic science; asthma and allergy; biophysics and cell biology; cancer; cardiovascular; nutrition and diabetes; genetics; infection and immunology; imaging and biomedical engineering; transplantation immunology; pharmaceutical science; physiology and women's health. We also have thriving research programmes in global health, and health and social care. Further information about the Faculty of Life Sciences and Medicine may be found at https://www.kcl.ac.uk/lsm/index.aspx

Within FoLSM, the School of Biomedical Engineering and Imaging Sciences is a cutting-edge research and teaching School dedicated to development, translation and clinical application within medical imaging and computational modelling technologies. Our objective is to facilitate research and teaching guided by clinical questions and is aimed at novelty, understanding of physiology and pathophysiology as well as development of new diagnostic tools and therapies. In this way, basic science can be rapidly translated into clinical applications (and vice versa). The School consists of eight research departments: Cardiovascular Imaging, Cancer Imaging, Early Life Imaging, Imaging Chemistry & Biology, Biomedical Computing, Surgical & Interventional Engineering, Imaging Physics & Engineering and Digital Twins for Healthcare.

The Research Department of Imaging Chemistry and Biology comprises a group of ca. 50 scientific and clinical researchers who drive translational radiopharmaceutical development, theragnostics, nanotechnology, metallomics, immuno-imaging, metabolic imaging, functional cardiac imaging, radiobiology, and engineering solutions for GMP radiopharmaceutical production. Embedding highly innovative scientists alongside clinical staff in a hospital environment has offered an unparalleled opportunity for translational impact that is being realised across the world-leading research infrastructure.

About The Role

The role is to develop novel radiopharmaceuticals and provide expertise as a developmental scientist in a multi-disciplinary team of chemists, radiochemists, (radio)biologists, preclinical molecular imaging scientists. Particular expertise is required in the development and validation of novel therapies using in vitro and in vivo models of cancer. This is a full-time post (35 hours per week) and you will be offered a fixed term contract of 3 months from start date.

About You

To be successful in this role, we are looking for candidates to have the following skills and experience:

Essential criteria

1. PhD level qualified in chemical or biomedical science (or relevant field).
2. Advanced knowledge in small molecule therapeutic drug development.
3. Expertise in development and optimisation of in vitro and in vivo efficacy assays.
4. Advanced skills in study/experimental design and analysis of complex research data.
5. Advanced knowledge of preclinical (in vitro and/or in vivo) validation.
6. Excellent inter-personal skills with an ability to work co-operatively in a multidisciplinary setting, working closely with biologists, chemists and radiochemists and GMP radiopharmaceutical production facility.
7. Possess excellent written and verbal communication skills and maintain accurate and up-to-date records of all findings, and to make these available to other members of the team

Desirable criteria

1. Advanced knowledge in the use of toxicity assay and translational criteria in drug development.
2. Basic knowledge of one or more aspects of molecular design in therapeutic radiopharmaceuticals and molecular imaging probes.
3. Knowledge in the design of imaging probe validation experiments using a combination of in vivo, in vitro and analytical methods.

Downloading a copy of our Job Description

Full details of the role and the skills, knowledge and experience required can be found in the Job Description document, provided at the bottom of the next page after you click "Apply Now". This document will provide information of what criteria will be assessed at each stage of the recruitment process.

Further Information

We pride ourselves on being inclusive and welcoming. We embrace diversity and want everyone to feel that they belong and are connected to others in our community. We are committed to working with our staff and unions on these and other issues, to continue to support our people and to develop a diverse and inclusive culture at King's.

We ask all candidates to submit a copy of their CV, and a supporting statement, detailing how they meet the essential criteria listed in the advert. If we receive a strong field of candidates, we may use the desirable criteria to choose our final shortlist, so please include your evidence against these where possible.

To find out how our managers will review your application, please take a look at our 'How we Recruit ' pages.