Postdoctoral Research Associate in Endocrinology and Metabolism

Corehr; London; On-site; GBP 44,000 - 47,000; Full time

Job summary

An exciting opportunity awaits for a Postdoctoral Research Associate in Endocrinology and Metabolism at a prestigious institution. This role involves contributing to a cutting-edge project funded by the Wellcome Trust, focusing on innovative imaging techniques and genetic engineering. You will collaborate with a dynamic team, leveraging your expertise in molecular biology to advance scientific knowledge in tissue microcirculation. If you are passionate about research and eager to make a significant impact in the field, this position is perfect for you. Join a diverse and inclusive community dedicated to excellence and innovation in biomedical research.

Qualifications

• PhD in biomedical sciences with expertise in molecular biology techniques.
• Experience with genetic manipulation and cell function assessment.

Responsibilities

• Develop acoustic reporters and validate them in vitro.
• Work as part of a team to advance imaging platforms.

Skills

Molecular cell biology techniques

Cell/tissue culture

qRT-PCR

Immunoassays

Immunohistochemistry

Genetic manipulation (Crispr, PiggyBAC)

Teamwork

Laboratory organization

Communication skills

Self-motivation

Education

PhD in biomedical sciences

Tools

Acoustic microscopy

Job description

Postdoctoral Research Associate in Endocrinology and Metabolism

Department: SCMMS Guys

About Us

The School of Cardiovascular and Metabolic Medicine & Sciences (SCMMS) is one of six schools that make up the Faculty of Life Sciences & Medicine (FoLSM) at King College London. The School drives translation of world-leading basic science into advances in clinical practices with activities focusing on the Cardiac Biomedicine Department of Diabetes and Vascular Biomedicine.

About the Role

Applications are invited for the position of Post-Doctoral Research Associate in the Department of Diabetes at King’s College London (KCL), working in the laboratories of Dr. Gavin Bewick.

This is a Wellcome Trust funded project led by Imperial College in collaboration with KCL and CALTECH entitled Dynamic 3D super-resolution ultrasound imaging of the micro-circulation and genetically encoded acoustic reporters in vivo.

Our vision is to generate and combine a powerful yet highly accessible in vivo imaging platform and genetically engineered contrast agents, enabling non-invasive whole body acoustic microscopy of tissue microcirculation and cellular and molecular biomarkers.

Initial funding is for an 18-month foundation phase with the possibility of a further 4.5 years funding for a scale-up phase. During the foundation phase, the successful candidate will work as part of a team and be responsible for developing acoustic reporters and their validation in vitro. They will have a PhD in a relevant biomedical sciences subject and have expertise in in vitro assessment of cell function and genetic engineering. Prior experience of gut stem cell biology and gut organoid culture would be a distinct advantage.

This is a full-time post (35 hours per week), and you will be offered a fixed-term contract until 31st May 2026.

About You

To be successful in this role, we are looking for candidates to have the following skills and experience:

1. Expertise in general molecular cell biology techniques such as cell/tissue culture, qRT-PCR, immunoassays, immunohistochemistry.
2. Experience with genetic manipulation e.g. Crispr, PiggyBAC.
3. Willing and able to work in a team.
4. Ability to keep clear and well-organised laboratory notes and records.
5. Ability to plan and prioritise workload.
6. Good communication (both written and verbal) and presentation skills.
7. Self-motivated, ability to work independently.

Additionally, experience with culturing mouse or human gut organoids and in vitro assessment of cell function including viability, apoptosis, proliferation, ATP generation, and secretory capacity is desirable.

Application Process

We ask all candidates to submit a copy of their CV and a supporting statement detailing how they meet the essential criteria listed in the advert. If we receive a strong field of candidates, we may use the desirable criteria to choose our final shortlist, so please include your evidence against these where possible.

To find out how our managers will review your application, please take a look at our ‘How we Recruit’ pages.

Further Information

We pride ourselves on being inclusive and welcoming. We embrace diversity and want everyone to feel that they belong and are connected to others in our community. We are committed to working with our staff and unions on these and other issues to continue to support our people and to develop a diverse and inclusive culture at King's.

Interviews are due to be held in mid-January 2025. We are not able to offer sponsorship for candidates who do not currently possess the right to work in the UK.

Grade and Salary: £44,105 - £46,421 per annum, including London weighting allowance.

Job ID: 102525

Post Date: 13-Dec-2024

Close Date: 06-Jan-2025

Contact Person: Dr. Gavin Bewick

Contact Details: [e-mail]