Postdoctoral Position in Cancer Biology

University of Liverpool; Liverpool; On-site; GBP 30,000 - 40,000; Full time

Job summary

The University of Liverpool offers a 24-month Postdoctoral position in Merino Lab, focusing on morphogen gradient scaling and its relevance in tumorigenesis. The role includes collaboration with Clatterbridge Cancer Centre and weekly discussions with the PI.

Responsibilities

• Understand the relevance of a novel scaling mechanism during human tumorigenesis.
• Engage with a multidisciplinary scientific environment.

Job description

We offer a Postdoctoral position (24 months) in Merino Lab at the University of Liverpool (ISMIB). This position is funded by the Springboard Award from the Academy of Medical Sciences. The position start date is September 2025.

The Question.

Currently, morphogen gradient scaling is one of the hottest fields in developmental biology. Scaling is fundamental, explaining how the machinery that controls pattern formation in development (the morphogens) can adapt so that organs of different sizes show morphological structures which are proportioned: the same developmental machinery can build the leg of a mouse, an elephant or a tumour.

We have recently found a novel scaling mechanism: Death-mediated scaling. If the gradient is not properly scaled, i.e., if the gradient is shorter than the tissue, then a death program is triggered. In this project, we propose to understand the relevance of this mechanism during human tumorigenesis in collaboration with the Clatterbridge Cancer Centre and Clinical Academics.

Our Lab/Institute Culture.

I maintain an open-door policy and aim to lead by example. You will meet the PI at least once per week to discuss new research avenues and brainstorm. You will have the opportunity to engage with the vibrant multidisciplinary scientific environment of the Institute of Systems, Molecular and Integrative Biology at the University of Liverpool, as well as activities run by our Postdoc Society. I promote equity and diversity in my research group and teaching roles, having completed EDI training at the University of Liverpool. These values are strongly aligned with those of our Institute and the University.

How to apply?

If you are interested in this position, please send a motivation letter and your CV to the PI.

Email: [e-mail]

Review of applications will start immediately.