Postdoctoral Fellow — Perinatal Genomics & Biomarkers

sanger; Hinxton; On-site; GBP 34,000 - 42,000; Full time

Job summary

The Wellcome Sanger Institute in the Cambridge area is seeking a highly motivated Postdoctoral Fellow to join the Martin group. The project aims to understand the genetic basis of early-life traits and to develop biomarkers for pregnancy complications and neonatal diseases, using large-scale sequencing and multi-omics data.

You will work on analyses of DNA sequence, methylation, and proteomic data from neonatal cohorts, collaborate with groups in the UK and Scandinavia, and contribute to

Qualifications

• Experience in statistical analyses of large-scale human genetic or other omic datasets, particularly DNA sequence data, methylation data and/or high-throughput proteomic data.

Responsibilities

• Analyze large-scale proteomic data from neonatal cohorts to identify biomarkers.
• Analyze sequence and genotype data from large birth cohorts to explore genetic influences on perinatal and neurodevelopmental traits.
• Investigate penetrance of variants associated with rare neurodevelopmental conditions and how genetic architecture varies across phenotype distributions.
• Develop biomarkers for pregnancy complications from cfDNA methylation-aware data and combine epigenetic and genetic information in integrated assays.

Job description

The Wellcome Sanger Institute in the Cambridge area is seeking a highly motivated Postdoctoral Fellow to join the Martin group. The project aims to understand the genetic basis of early-life traits and to develop biomarkers for pregnancy complications and neonatal diseases, using large-scale sequencing and multi-omics data.

You will work on analyses of DNA sequence, methylation, and proteomic data from neonatal cohorts, collaborate with groups in the UK and Scandinavia, and contribute to