Postdoc: Membrane Biophysics & Alveolus-on-a-Chip

Imperial Enterprise; Greater London; Hybrid; GBP 45,000 - 49,000; Full time

Benefits offered by this job

39 days off per year

Excellent research facilities

Job summary

Imperial College London invites applications for a 24-month Postdoctoral Research Associate focusing on cell membrane biophysics. You will study how cholesterol modulates GLP1R signalling using advanced microscopy and develop an Alveolus-on-a-Chip platform to model alveolar epithelium under breathing-mimetic conditions.

The role requires a PhD in pharmacology, biophysics, cell biology or bioengineering and strong microscopy and data analysis skills.

Qualifications

• PhD in pharmacology, biophysics, cell biology or bioengineering.
• Proven experience in membrane biophysics or GPCR signalling research.
• Proficiency with advanced fluorescence microscopy techniques.

Responsibilities

• Lead investigations into cholesterol-driven GLP1R signalling and conformational dynamics.
• Design, fabricate and validate an Alveolus-on-a-Chip platform under breathing-mimetic conditions.
• Integrate molecular pharmacology findings with organ-on-chip systems for tissue-level insights.
• Collaborate with international partners across structural pharmacology and computational modelling.

Skills

Membrane biophysics

GPCR signalling

Fluorescence microscopy

Single-molecule imaging

Advanced microscopy

Bioengineering

Data analysis

Team collaboration

Education

PhD in pharmacology/biophysics/cell biology/bioengineering

Tools

ImageJ

MATLAB

FLIM/phasor analysis

Job description

Imperial College London invites applications for a 24-month Postdoctoral Research Associate focusing on cell membrane biophysics. You will study how cholesterol modulates GLP1R signalling using advanced microscopy and develop an Alveolus-on-a-Chip platform to model alveolar epithelium under breathing-mimetic conditions.

The role requires a PhD in pharmacology, biophysics, cell biology or bioengineering and strong microscopy and data analysis skills.