Post Doctoral Researcher

University of Oxford; Oxford; On-site; GBP 34,000 - 42,000; Full time

Benefits offered by this job

Athena Swan Gold award

Ten paid days of professional developm

Funding for training courses

Visa renewal fee assistance

Job summary

University of Oxford’s Gupta Lab in the Department of Paediatrics invites applications for a Post Doctoral Researcher to join the Institute of Development and Regenerative Medicine on the Old Road Campus. The role focuses on bioconjugate chemistry to develop next-generation delivery platforms for nucleic acid therapeutics.

You will collaborate with chemists, molecular biologists, and clinicians to design and synthesize chemical conjugates, assess stability and delivery efficacy in vitro and in

Qualifications

• PhD with demonstrable organic chemistry and molecular biology skills.
• Experience in designing experiments and analyzing data in a demanding research environment.
• Ability to collaborate across chemistry, biology and clinical teams.

Responsibilities

• Design and synthesize chemical conjugates for nucleic acid delivery.
• Evaluate stability, specificity and delivery efficacy in vitro and in vivo.
• Collaborate with chemists, biologists and clinicians to advance translational research.

Skills

Bioconjugate chemistry

Organic chemistry

Molecular biology

Education

PhD

Job description

Post Doctoral Researcher

We have an exciting opportunity to join the Gupta Lab in the Department of Paediatrics as our Post Doctoral Researcher. The successful candidate will join Dr. Dhanu Gupta at the Institute of Development and Regenerative Medicine on the Old Road Campus. The Gupta Lab at the University of Oxford is seeking a highly motivated Postdoctoral Researcher with expertise in bioconjugate chemistry to develop next-generation delivery platforms for nucleic acid therapeutics.

The successful candidate will work closely with chemists, molecular biologists, and clinicians to design and synthesize chemical conjugates for nucleic acid delivery. This will include linker chemistry, oligonucleotide modification, and bioconjugation to peptides, lipids, polymers, antibodies, or extracellular vesicles. The postholder will evaluate stability, specificity, and delivery efficacy of these conjugates in vitro and in vivo.

This role represents a unique opportunity to contribute to translational therapeutic development at the interface of chemistry, biology, and medicine. You will be working in a growing department within the Medical Sciences Division. The Department of Paediatrics is a world leader in child health research and hosts internationally renowned research programmes in drug development, gastroenterology, haematology, HIV, immunology, neuroimaging, neuromuscular diseases and vaccinology.

This position is offered full-time on a fixed-term contract initially for one year with the possibility to extend provided further external funding is available. This role may be eligible for a Global Talent visa.

The Department of Paediatrics holds the Athena Swan Gold award (a national gender equality charter) acknowledging the innovative policies and practices developed across the department.

• We encourage staff to develop their skills by offering all staff ten paid days of professional development each year.
• and have a policy where staff can apply to receive funding for further training courses to support their professional development.
• For staff on work visas, we also offer financial assistance towards visa renewal fees.

You will have a PhD, with proven and demonstrable organic chemistry and molecular biology skills. You will be able to design the experiments, execute the experiment using various molecular biology techniques, and help analyse the data. You will have highly effective verbal and written communication skills with all level of staff and an ability to operate effectively in a demanding research environment.