Platform Engineer (HPC / High Performance Computing)

Genomics England; London; Hybrid; GBP 71,000 - 90,000; Full time

Job summary

A leading company in genomic healthcare seeks an experienced AWS HPC Platform Engineer to enhance their cloud capabilities. The role involves mentoring engineers, managing HPC clusters, and ensuring optimal performance and cost efficiency. With a focus on collaboration and innovation, you will play a key role in advancing genomic research and healthcare solutions.

Benefits

Generous leave

Flexible working

Pension

Learning budgets

Health & wellbeing support

Qualifications

• Fluency in data storage services like S3 and data lakes.
• Expertise in Infrastructure as Code with Terraform and CI/CD pipelines.

Responsibilities

• Lead implementation of AWS best practices and mentor engineers.
• Maintain and optimize the live HPC cluster in AWS.
• Implement cost optimization strategies for AWS HPC operations.

Skills

Problem Solving

Teamwork

Communication

Education

Deep hands-on experience with building compute environments

Tools

Terraform

GitLab

AWS

Ansible Tower

Job description

Platform Engineer (HPC / High Performance Computing)

Employer: Genomics England | Location: London, United Kingdom | Salary: Competitive | Closing date: 18 May 2025

View more categories | View less categories | Discipline: Engineering, Software Engineering | Position Type: Permanent | Hours: Full Time | Result Type: Jobs

Company Description

Genomics England partners with the NHS to provide whole genome sequencing diagnostics. We also equip researchers to find the causes of disease and develop new treatments — with patients and participants at the heart of it all.

Our mission is to continue refining, scaling, and evolving our ability to enable others to deliver genomic healthcare and conduct genomic research.

We are accelerating our impact and working with patients, doctors, scientists, government, and industry to improve genomic testing, and help researchers access the health data and technology they need to make new medical discoveries and create more effective, targeted medicines for everybody.

Job Description

We are seeking an experienced AWS HPC Platform Engineer with a proven track record. You will lead the implementation of AWS best practices across a team of engineers developing their expertise in AWS platform engineering. Your role includes supporting the live service HPC cluster in AWS, ensuring stability and performance, and collaborating closely with our infrastructure architect on core cloud-related operational activities.

Key Responsibilities

• Leadership & Mentorship: Guide and mentor engineers, promote AWS best practices, and drive automation standards.
• HPC Cluster Support: Maintain and optimise the live HPC cluster in AWS, collaborating with the Infrastructure Architect.
• Data Platform & Tools Support: Manage tools like LSF RTM, Athena databases, and workflows, ensuring seamless integration and performance.
• Infrastructure as Code (IaC): Align IaC strategies using Ansible Tower and GitLab Pipelines for AWS and on-prem environments.
• Benchmarking & Healthchecks: Develop and implement benchmarking and healthchecks leveraging AWS capabilities.
• IOPS Monitoring Tool Integration: Support rollout of Mistrel/Breeze tools in AWS, ensuring connectivity with on-prem and AWS HPC environments.
• Cost Optimisation: Implement strategies for cost-efficient AWS HPC operations.
• Vulnerability Patching: Develop solutions for vulnerability patching, especially for large EC2 instances.
• S3 Integration: Support integration of S3 into Double Helix for cloud storage expansion.
• DRAGEN F2 Integration: Design and support DRAGEN F2 implementation, including AMIs.

Qualifications

• Deep hands-on experience with building compute environments (GPUs, CPUs) using cloud services.
• Fluency in data storage services (S3, mount-point, data lakes, Lustre).
• Expertise in Infrastructure as Code (IaC) with Terraform and CI/CD pipelines with GitLab.
• Strong problem-solving skills and strategic thinking.
• Excellent teamwork and communication skills.

Additional Information

Salary from: £71,500

We offer a comprehensive benefits package, including generous leave, flexible working, pension, learning budgets, recognition programs, health & wellbeing support, and more.

Genomics England is committed to diversity, inclusion, and equal opportunity. We promote a respectful environment where everyone can thrive regardless of background or identity.

Our blended working model allows most staff to work remotely part of the time, with office locations in Canary Wharf, Cambridge, and Leeds. Most roles require a minimum of 2 days per month in the office.

All successful candidates will undergo a DBS check, and applicants must disclose any previous offences.