PhD Studentship: Environmental AMR Modeling & Validation

University of Birmingham; Birmingham; Sur place; GBP 18 000 - 20 000; Plein temps

Avantages offerts par ce poste

Annual stipend

Home-fee level tuition fees

Research Training Support Grant

Résumé du poste

University of Birmingham is offering a CENTA3 DLA funded PhD studentship that combines mathematical modelling with environmental microbiology to predict selection of antibiotic resistance in natural waters. You will develop models based on simple lab experiments and validate them in flume mesocosms at UKCEH Wallingford, integrating diversity, predation, and substrate effects with in situ river tests.

The project includes a stipend, home-fee level tuition fees, and a Research Training Support

Qualifications

• Academic requirements: at least a 2:1 at UK BSc level or a pass at UK MSc level or equivalent.

Responsabilités

• Develop mathematical models based on results from simple lab experiments and then create the complexity in the model by including the effects of diversity, predation, low substrate concentrations etc, ultimately predicting at which concentration selection happens in the environment.
• This will be coupled with experiments under natural conditions to test and validate the model, in flume mesocosms that can mimic river conditions in the lab at UKCEH Wallingford and also in situ in rivers.
• Such a validated mathematical model that can predict the risk of selection under environmental conditions is hugely important because it is impossible to expose thousands of different pathogenic and environmental bacteria with various (combinations) of resistances to many levels of hundreds of potentially selective antibiotics and other compounds under a variety of relevant environmental conditions.

Formation

2:1 UK BSc or MSc pass

Description du poste

University of Birmingham is offering a CENTA3 DLA funded PhD studentship that combines mathematical modelling with environmental microbiology to predict selection of antibiotic resistance in natural waters. You will develop models based on simple lab experiments and validate them in flume mesocosms at UKCEH Wallingford, integrating diversity, predation, and substrate effects with in situ river tests.

The project includes a stipend, home-fee level tuition fees, and a Research Training Support