PhD in Targeted Protein Degradation Tools - Cambridge

University of Cambridge; Cambridge; On-site; GBP 18,000 - 21,000; Full time

Job summary

The Department of Pharmacology at the University of Cambridge, in partnership with AstraZeneca, offers a funded PhD studentship focused on proteasome-targeting tools and novel approaches for Targeted Protein Degradation (TPD).

You will join Dr Catherine Lindon's lab, work independently with a supervisory team, and contribute to discovering Midnolin binders and engineering degrader tools for oncology targets within a four-year program.

Qualifications

• Degree in biochemistry or related field.
• Strong interest in proteasome biology and protein degradation.
• UK university degree or equivalent, with evidence of laboratory training.

Responsibilities

• Join the lab of Dr Catherine Lindon and contribute to developing proteasome-targeting tools.
• Collaborate with a supervisory team including AstraZeneca scientists and Cambridge academics.
• Design experiments and generate data to advance a Midnolin-based degrader platform.

Skills

Biochemistry

Cell biology

Targeted Protein Degradation

Education

Bachelor's degree (UK 2:1) or equivalent

Job description

The Department of Pharmacology at the University of Cambridge, in partnership with AstraZeneca, offers a funded PhD studentship focused on proteasome-targeting tools and novel approaches for Targeted Protein Degradation (TPD).

You will join Dr Catherine Lindon's lab, work independently with a supervisory team, and contribute to discovering Midnolin binders and engineering degrader tools for oncology targets within a four-year program.