PhD: Decode & Design DNA Replication with Genome AI

University of East Anglia; Norwich; On-site; GBP 24,000 - 29,000; Full time

Benefits offered by this job

Fully funded PhD

4-year studentship

Tuition fees paid

Job summary

University of East Anglia and the NRPDTP invite applications for a fully funded PhD project exploring how DNA replication origins are encoded and regulated within genomes. You will combine AI-driven genome models with high-throughput experiments to uncover governing rules and design synthetic DNA sequences for testing in yeast.

The project is hosted at the Earlham Institute within Norwich Research Park, offering training in machine learning, genome engineering, CRISPR editing, and advanced

Qualifications

• At least UK equivalence Bachelors (Honours) 2:1.
• IELTS 6.5 overall, 6 in each category.

Responsibilities

• Develop predictive models of replication origin function.
• Design hundreds of synthetic DNA sequences.
• Test performance in yeast using nanopore sequencing technologies.
• Work at the interface of computational biology, synthetic biology and genomics.

Skills

Computational biology

Genomics

Machine learning

Genome engineering

CRISPR

Education

UK BA/BSc 2:1 equivalent

Tools

Nanopore sequencing

CRISPR genome editing

Automation

Job description

University of East Anglia and the NRPDTP invite applications for a fully funded PhD project exploring how DNA replication origins are encoded and regulated within genomes. You will combine AI-driven genome models with high-throughput experiments to uncover governing rules and design synthetic DNA sequences for testing in yeast.

The project is hosted at the Earlham Institute within Norwich Research Park, offering training in machine learning, genome engineering, CRISPR editing, and advanced