Pharmacometrics R Programmer - PK/PD Data

ICON Clinical Research; Reading; On-site; GBP 65,000 - 90,000; Full time

Benefits offered by this job

Various annual leave entitlements

Health insurance offerings

Competitive retirement planning

Global Employee Assistance Programme

Life assurance

Flexible country-specific benefits

Job summary

ICON plc is seeking a Pharmacometrics Support Programmer to join a global FSP team in Reading. You will develop and QC NONMEM PK/PD datasets, ensure data quality and regulatory readiness, and collaborate across Data Management, Statistical Programming, and Bioanalysis to drive model-informed drug development.

The role requires strong R programming expertise, SDTM/ADaM/CDISC knowledge, and a track record in PK/PD data preparation and standardisation within pharma or CRO settings.

Qualifications

• Bachelor's degree in a Life Science, Health Science, Statistics, Computer Science, IT, or related discipline.
• Minimum 6 years' experience in pharmaceutical, biotechnology, or CRO industry.
• Strong programming in R and experience developing NONMEM PK/PD datasets.
• Working knowledge of SDTM, ADaM, and CDISC standards.
• Experience supporting NONMEM file creation, quality control and submissions.

Responsibilities

• Develop and quality control NONMEM PK/PD datasets using SDTM and ADaM sources.
• Deliver accurate, complete, submission-ready datasets for modelling.
• Quality review of internally and externally produced NONMEM datasets.
• Collaborate with cross-functional teams to resolve data issues and meet timelines.
• Prepare regulatory submission datasets per pharmacometrics guidelines.
• Quality control testing of customised R packages for standardised workflows.
• Develop and maintain testing frameworks for departmental R tools and packages.
• Identify data discrepancies and opportunities for automation and efficiency.
• Contribute to pharmacometric standardisation initiatives and SOP adherence.

Skills

R programming

Data quality assurance

Education

Bachelor's degree in Life Science / Health Science / Statistics / Computer Science / IT

Tools

NONMEM

SDTM/ADaM/CDISC

Job description

ICON plc is seeking a Pharmacometrics Support Programmer to join a global FSP team in Reading. You will develop and QC NONMEM PK/PD datasets, ensure data quality and regulatory readiness, and collaborate across Data Management, Statistical Programming, and Bioanalysis to drive model-informed drug development.

The role requires strong R programming expertise, SDTM/ADaM/CDISC knowledge, and a track record in PK/PD data preparation and standardisation within pharma or CRO settings.