Operator Grade 6 - SF&A (Nights - Friday to Sunday)

AstraZeneca; Macclesfield; On-site; GBP 30,000 - 40,000; Full time

Job summary

A global BioPharmaceutical leader in Macclesfield is seeking an Operator Grade 6 to join their Syringe Fill & Assembly team. The role involves operating key manufacturing equipment for sterile oncology drugs, ensuring compliance with stringent SHE and GMP standards. Candidates should have A-levels in a related field and experience in a controlled environment. This position offers competitive salary and the chance to contribute to life-changing treatments in a collaborative and inclusive workplace.

Benefits

Competitive salary

Comprehensive benefits

Focus on sustainability and inclusivity

Qualifications

• A-levels in a Science, Technology or Maths discipline or equivalent.
• Experience in GMP and SHE controlled environments.
• Operational knowledge of specific line equipment.

Responsibilities

• Set up and operate specific equipment on the Packing Line.
• Complete electronic documentation accurately.
• Conduct cleaning operations in APA and White Area.

Skills

Attention to detail

Ability to operate sophisticated machinery

Problem solving skills

Collaboration

Education

A-levels in Science, Technology or Maths

Degree in Science, Technology or Maths

Tools

Syringe fill machines

Labeller

Pouch sealing machines

Job description

Operator Grade 6 - SF&A (Nights - Friday to Sunday)

Location: Macclesfield, UK

Competitive salary and benefits

Permanent Nights - 36 hours per week

Are you ready to make a difference in the world of medicine? At AstraZeneca, we transform scientific ideas into life-changing treatments. As a global BioPharmaceutical leader, we focus on discovering, developing, and commercialising prescription medicines for serious diseases. Join us as an Operator in our Syringe Fill & Assembly (SF&A) team, where you'll play a crucial role in the manufacturing process of a sterile Oncology drug on our cutting-edge packing line. Embrace the challenge of working in a highly regulated environment, ensuring compliance with Safety, Health and Environmental (SHE) standards, current Good Manufacturing Practice (cGMP), and AstraZeneca's high standards.

Accountabilities:

• Set up and operate specific equipment such as syringe fill, labeller and pouch sealing machines and perform safety checks on the Packing Line.
• Complete electronic documentation with precision.
• Initiate the line gassing cycle using hydrogen peroxide.
• Perform hatch transfers of consumables, components, and various equipment.
• Perform minor interventions and participate in major interventions under aseptic conditions.
• Conduct cleaning operations in general APA and White Area locations.
• Perform equipment performance checks.
• Carry out environmental and personal monitoring.

Essential Skills/Experience:

• A-levels in a Science, Technology or Maths discipline or equivalent
• Previous experience of following SOP's in a SHE and GMP controlled environment with a strong attention to detail
• Operational knowledge of specific line equipment
• Computer literate and comfortable in a highly digital environment
• Ability to operate sophisticated machinery and lift and transport equipment, products and tools
• Ability to learn and adapt to changing operational requirements
• Ability to undertake core tasks independently, with a focus on attention to detail
• Able to work collaboratively
• Is intrinsically motivated
• Proven problem solving skills and flexibility required to balance conflicting priorities

Desirable Skills/Experience:

• Recent experience working in a sterile manufacturing environment
• Experience of Manufacturing Excellence/Lean ways of working including problem solving and continuous improvement techniques
• Degree in a Science, Technology or Maths discipline or equivalent

Please note: This position is internally aligned to SA91 G6.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, three shifts per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

At AstraZeneca, you'll find yourself part of an innovative team committed to sustainability goals that make a real impact on society. With our ambitious targets like achieving Zero Carbon by 2025, you'll contribute to pioneering efforts that extend beyond patient care. Our inclusive environment fosters collaboration and growth, offering opportunities to expand your skills and knowledge while making a meaningful difference.

Ready to take the next step? Apply now and be part of our journey to transform medicine for patients worldwide!

Date Posted

07-Aug-2025

Closing Date

19-Aug-2025 Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.