Onsite Cambridge NGS Scientist II – MRD & cfDNA

NeoGenomics Laboratories, Inc.; Babraham; On-site; GBP 45,000 - 65,000; Full time

Job summary

NeoGenomics Laboratories, Inc. in Cambridge, UK, seeks a Scientist for a fixed-term contract through 2027 to develop MRD detection tech from early research through optimization and viability assessment.

This onsite role requires hands-on NGS and collaboration with computational colleagues. You will refine experiments, perform complex library prep, cfDNA extractions, and analyze sequencing data, while maintaining precise records for regulatory purposes.

Qualifications

• PhD strongly preferred in Life, Physical or Computer Science.
• At least two years of applied experience with Molecular (NGS) platform and assay development.
• Hands-on next generation sequencing library preparation experience is essential.
• Experience with cell-free DNA, low input library preparation, UMI sequencing, or other error suppression approaches is strongly preferred.
• Experience in cancer diagnostics, liquid biopsy or ctDNA analysis preferred.
• Strong practical laboratory skills, particularly in NGS library construction and quantitative molecular biology.

Responsibilities

• Refine and execute program of research and optimization experiments for a novel cell free DNA MRD detection method.
• Independently perform complex and novel library preparation and next generation sequencing workflows.
• Perform supporting work such as blood processing and cfDNA extractions.
• Diagnose and resolve experimental problems, distinguishing true method limitations from technical artifact, contamination, or workflow error; escape appropriately and in a timely manner.
• Analyze and interpret sequencing data in collaboration with computational colleagues, contributing to the definition of analytical requirements for the method.
• Maintain complete, accurate and contemporaneous experimental records to a standard suitable for regulatory and patent purposes.

Skills

Hands-on lab skills

Troubleshooting complex experiments

Collaboration with computational team

Data analysis mindset

Education

PhD in Life/Physical/Computer Science

Tools

NGS library preparation

cfDNA extraction / low input

UMI sequencing / error suppression

Job description

NeoGenomics Laboratories, Inc. in Cambridge, UK, seeks a Scientist for a fixed-term contract through 2027 to develop MRD detection tech from early research through optimization and viability assessment.

This onsite role requires hands-on NGS and collaboration with computational colleagues. You will refine experiments, perform complex library prep, cfDNA extractions, and analyze sequencing data, while maintaining precise records for regulatory purposes.