Oncology Clinical Research Associate: Site & Quality

AstraZeneca; Cambridge; On-site; GBP 55,000 - 85,000; Full time

Job summary

AstraZeneca is seeking a Clinical Research Associate (oncology) to drive site performance and data quality from initiation through close-out. You will collaborate with investigators, site staff and cross-functional teams, ensuring regulatory readiness and inspection preparation across studies.

The role emphasizes risk-based monitoring, timely reporting of safety events, and maintaining high standards of care. A strong background in ICH-GCP and drug development is required, with travel as needed.

Qualifications

• Bachelor’s degree in life sciences or equivalent.
• Excellent knowledge of ICH-GCP and basic GMP/GDP.
• Good knowledge of local regulations.
• Solid understanding of drug development processes.
• Strong communication and collaboration skills.
• Ability to travel nationally/internationally as required.

Responsibilities

• Identify and select investigators and sites to maximise feasibility, quality and delivery.
• Lead or support start-up activities including regulatory submissions and ethics approvals.
• Monitor sites and manage initiation to close-out per monitoring plans.
• Ensure training and inspection readiness of site staff and investigators.
• Support patient recruitment and monitor site performance and risk.
• Review data quality, manage source data and maintain CTMS/eTMF accuracy.
• Collaborate with stakeholders to resolve issues and prepare for audits and inspections.
• Drive continuous improvement in trial delivery and data integrity.

Skills

Bachelor’s degree

ICH-GCP knowledge

Regulatory knowledge

Data management understanding

Communication skills

Travel readiness

Education

Bachelor’s degree in life sciences

Job description

AstraZeneca is seeking a Clinical Research Associate (oncology) to drive site performance and data quality from initiation through close-out. You will collaborate with investigators, site staff and cross-functional teams, ensuring regulatory readiness and inspection preparation across studies.

The role emphasizes risk-based monitoring, timely reporting of safety events, and maintaining high standards of care. A strong background in ICH-GCP and drug development is required, with travel as needed.