Molecular Scientist I

ANGLE plc; Guildford; On-site; GBP 30,000 - 60,000; Full time

Job summary

An established industry player is seeking a Molecular Scientist I to join their dynamic team in Guildford. This role offers the opportunity to work hands-on in a laboratory environment, contributing to the development of innovative clinical diagnostic products. The position emphasizes collaboration and excellence, with a focus on molecular biology techniques such as dPCR and NGS. As part of a forward-thinking company, you will be at the forefront of translating cutting-edge research into practical applications, making a significant impact in the field of cancer diagnostics. If you are passionate about science and eager to make a difference, this role is perfect for you.

Benefits

Training and Development Opportunities

Competitive Benefits Package

Qualifications

• Masters in Life Sciences with 2+ years of lab experience in molecular biology.
• Hands-on competency in dPCR, qPCR, and NGS required.

Responsibilities

• Conduct hands-on laboratory work in Molecular Biology.
• Manage development projects within a strict quality management system.

Skills

Molecular Biology

dPCR

qPCR

NGS

Project Management

Quality Compliance

Education

Masters in Life Sciences

Tools

Quality Management System (ISO13485)

Job description

About ANGLE:

ANGLE is a world-leading liquid biopsy company commercialising a patent protected platform technology that can capture rare circulating tumour cells (CTCs) from blood, in a minimally invasive way, for downstream analysis.

ANGLE's Parsortix system is FDA cleared for its intended use in metastatic breast cancer and is currently the first and only FDA cleared medical device to harvest intact circulating cancer cells from blood. Parsortix technology comprises a microfluidic device that captures CTCs from blood based on their size and compressibility. CTCs are cancer cells that have detached from the primary tumour and entered the blood circulation, and they play a critical role in initiating metastasis. Once harvested, the CTCs can be comprehensively analysed to provide a wealth of information about the patient's tumour, advancing cancer research and potentially personalized medicine. This technology has the potential to deliver profound improvements in clinical and health economic outcomes.

ANGLE has established a CTC harvest and analysis service from our UK-based Clinical Laboratory based in Guildford for customers worldwide. In alignment with company priorities, we plan to rapidly expand our services to include molecular profiling of CTCs and ctDNA using digital PCR and NGS to add to our image-based assays.

Join our Team:

This is an exciting time at ANGLE and our team in Guildford are looking for a Scientist I Molecular. The Molecular Scientist I contributes to the management of the laboratory and development of clinical diagnostic products. The job is laboratory based working in a multi-disciplinary team.

At ANGLE, we foster a dynamic, entrepreneurial approach to translating leading-edge translational research into clinical diagnostics. We promote a culture of collaboration and shared excellence while encouraging an open and honest exchange of ideas.

We are always in search of potential employees who share our vision and want to make a difference today. In your submission, please describe your background and what you can bring to our team along with attaching your resume.

Principal Accountabilities:

1. Hands-on laboratory work, primarily in the area of Molecular Biology.
2. Provide scientific and technical support to programmes and projects.
3. Responsible for on-time and on-budget delivery of work packages within a project, including timely reporting of progress on projects and on metrics to monitor and mitigate risk and to ensure product deadlines are met.
4. Responsible for quality and regulatory compliance of work undertaken.
5. Independently keep a current knowledge base in relevant areas of scientific and technical research.
6. Manage the day to day running of assigned development projects within the Quality Management System (ISO13485);
7. Undertake additional ad hoc / project work as required.

Qualifications, Experience, Knowledge and Attributes:

1. Masters in Life Sciences, with at least 2 years of relevant laboratory experience or equivalent in molecular biology, preferably gained in the in vitro diagnostics industry in diagnostic assay development/validation;
2. Demonstrated expertise and hands-on competency in dPCR, qPCR and/or NGS;
3. Experience working to strict quality standards such as Medical Device regulations and standards including, but not limited to, 21 CFR 820, ISO 13485, 93/42/EEC, IVD 98/79 EC, ISO14971, GMP, GLP, QSR. A strong understanding of the importance of accurate record keeping within a strictly controlled quality system is essential;
4. Organisational skills and the ability to rapidly prioritise tasks in response to unexpected opportunities or risks;
5. Manage and deliver product development projects to agreed performance specifications, on time and within budget;

Job Requirements:

Due to the nature of the role, our requirement is for this position to be Guildford based 5 days per week.

As a member of our highly skilled team you will receive opportunities for training and development and a competitive benefits package.

Please let us know if you require disability-related accommodation during the recruitment process so that we can work with you to meet your needs.

Furthermore, please be advised that if you submit an application to us for this position, your application and personal details will be processed in accordance with our Data Privacy Notice for Job Candidates.

Important notice to Employment Businesses/ Agencies:

ANGLE does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact our ANGLE recruitment team to obtain prior written authorisation before referring any candidates. In the absence of such written authorisation being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of ANGLE. ANGLE shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.