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A leading genomics company is seeking a Lead Bioinformatics Scientist to drive R&D projects in sequencing technologies. This role involves collaborating across teams to establish bioinformatics milestones, leading data analysis, and ensuring the quality of sequencing data. Candidates should have a strong background in bioinformatics, programming skills in Python or R, and a Masters or PhD in a related field. The position is remote within the UK, and is part of a company committed to diversity and inclusion.
The Staff Bioinformatics Scientist will work alongside engineering, chemistry and assay teams on R&D projects delivering new sequencing platforms and technologies. In this role, the Staff Scientist will represent bioinformatics in cross-functional programs:
Defining bioinformatics milestones and requirements · Leading data analysis activities
Developing novel tools and pipelines
Contributing to project strategy
In addition to strong bioinformatics and programming skills, this position requires a high degree of initiative and cross-team collaboration, as well as a thorough understanding of the product development process.
Responsibilities:
Represent bioinformatics in R&D projects across multiple sites for the design, development and validation of novel sequencing products.
Lead the data quality and bioinformatics function in a research or product development team, including defining milestones, establishing work priorities, and delegating tasks to other sub-team members as needed.
Collaborate with subject matter experts across R&D functions to understand, define, and communicate sequencing technology requirements for research and clinical applications.
Contribute to the planning and execution of a comprehensive strategy for assessing quality of data from existing and novel sequencing technologies.
Lead the analysis, integration, modelling and interpretation of experimental data. ·
Translate complex analysis results into actionable recommendations for technology development and improvement.
Present results clearly and effectively to both technical and non-technical stakeholders.
Stay current on the latest publications and relevant research and identify established methods that should be incorporate into method development.
Listed responsibilities are an essential, but not exhaustive list, of the usual duties associated with the position. Changes to individual responsibilities may occur due to business needs.
Requirements:
· Proficient programming skills and experience with several programming
languages, such as Python, R, etc.
· Strong understanding of next-generation sequencing technologies and their
underlying principles.
· Experience working with Unix/Linux and High Performance Computing (HPC)
environments.
· Strong data analysis and visualization skills.
· Proficiency with common bioinformatics algorithms and methods. Hands on
experience of quality control and analysis of data generated from a variety of
omics, such as WGS, scRNA, somatic profiling, proteomics, methylation, etc.
· Excellent communication skills and a proven track record of collaborating with
diverse teams.
Desired:
· Experience working with cloud environments (e.g., AWS).
· Experience with workflow management languages, such as Nextflow, WDL, etc.
· Familiarity with containerization tools, such as Docker, and similar technologies.
Education:
Masters/PhD in bioinformatics, computer science, data science, engineering, mathematics or equivalent