Lead Scientist, AI-Driven Cheminformatics & Drug Design

GlaxoSmithKline plc; Stevenage; In loco; GBP 90.000 - 130.000; Tempo pieno

Descrizione del lavoro

GlaxoSmithKline plc in the DAPS Cheminformatics group seeks a Principal Scientist to develop ML-driven cheminformatics and computational chemistry methods for small molecule discovery. You will embed predictive models into decision workflows and work across multidisciplinary teams.

The role is based in Stevenage with relocation to Cambridge planned by 2029; strong programming skills and PhD preferred. You will present validated results to internal and external groups.

Competenze

• PhD or MSc in Cheminformatics or related field.
• Experience collecting, mining, and analysing complex biological/chemical data to build predictive models.
• Broad knowledge of ML, computational chemistry, and cheminformatics methods.
• Programming experience in Python, Java, C/C++, or R.

Mansioni

• Build, validate and deploy cheminformatics and machine learning models to inform go/no-go decisions across drug-discovery programmes.
• Integrate with drug discovery teams to embed predictive models into decision making for non-experts.
• Prototype workflows combining LLM-based reasoning with cheminformatics tools and experimental data to accelerate design cycles.
• Develop production-quality code implementing state-of-the-art cheminformatics and quantum chemistry methods.
• Prepare and present validation results and capability developments to internal and external groups.

Conoscenze

Cheminformatics

Machine Learning

Computational Chemistry

Python

Java

C/C++

R

Formazione

PhD/MSc in Cheminformatics

Life Sciences

Strumenti

ChemAxon

RDKit

Pipeline Pilot

KNIME

Descrizione del lavoro

GlaxoSmithKline plc in the DAPS Cheminformatics group seeks a Principal Scientist to develop ML-driven cheminformatics and computational chemistry methods for small molecule discovery. You will embed predictive models into decision workflows and work across multidisciplinary teams.

The role is based in Stevenage with relocation to Cambridge planned by 2029; strong programming skills and PhD preferred. You will present validated results to internal and external groups.