Lead Large Molecule Bioanalysis Specialist

ACM UK; York and North Yorkshire; On-site; GBP 70,000 - 90,000; Full time

Job summary

ACM UK is seeking a Technical Specialist in York to lead development, validation and lifecycle management of LBAs (PK/TK, ADA, biomarkers) supporting GLP/GCP studies. You will drive assay design, data integrity and regulatory readiness in a fast-paced environment.

You will mentor scientists, ensure regulatory compliance, manage equipment and CSV, and drive continuous improvement across bioanalytical platforms such as ELISA and MSD.

Qualifications

• BSc or higher in a relevant scientific subject.
• Minimum 5 years’ experience in a bioanalytical laboratory.
• Experience with large molecule bioanalysis and LBA techniques.
• Regulatory knowledge of GLP/GCP guidance.

Responsibilities

• Design, develop, validate, and implement robust LBA methods in line with regulatory guidance.
• Independently manage method development, transfer, validation, and study support activities.
• Lead troubleshooting of assays and instrumentation, providing timely support to lab teams.
• Ensure GLP/GCP compliance, oversee CSV and software validation activities.
• Provide hands-on technical guidance and mentorship to laboratory scientists.

Skills

LBA method development

GLP/GCP compliance

Biomarker assays

Troubleshooting

Method validation

Education

Bachelor's degree in a relevant scientific subject

Higher degree preferred

Tools

ELISA

MSD/ELISA platforms

CSV/QA systems

Job description

ACM UK is seeking a Technical Specialist in York to lead development, validation and lifecycle management of LBAs (PK/TK, ADA, biomarkers) supporting GLP/GCP studies. You will drive assay design, data integrity and regulatory readiness in a fast-paced environment.

You will mentor scientists, ensure regulatory compliance, manage equipment and CSV, and drive continuous improvement across bioanalytical platforms such as ELISA and MSD.