Lead Antibody Kinetics & Developability Scientist

LabGenius Therapeutics; Greater London; On-site; GBP 90,000 - 120,000; Full time

Benefits offered by this job

Stock options

Annual bonus

Life assurance (3x salary)

Income protection

Private medical insurance

Gym discount

Cycle to work

25 days annual leave

Job summary

LabGenius Therapeutics, based in London, seeks a kinetics expert to lead antibody binding characterization and to build a world-class platform from the ground up. You will drive high-resolution kinetic screening and hands-on development of Biacore/BLI workflows, feeding ML models with precise measurements.

You’ll own automated biophysical assays, stress-test binders for clinical readiness, and work with data science to translate sensor data into actionable insights for lead optimization.

Qualifications

• PhD or MSc with hands-on wet-lab experience in antibody characterization.
• Expertise in SPR or BLI with kinetic assay design and sensor chip selection.
• Experience managing large-scale screening campaigns with data integrity.
• Proficient in data analysis tools and binding models.
• Experience with thermostability assays and analytical protein techniques.
• Ability to present complex kinetic data to non-experts.

Responsibilities

• Design, implement, and own our antibody binding platform and instrumentation selection.
• Lead high-resolution kinetic screening to determine kon, koff, KD for large panels.
• Perform epitope binning/mapping to support IP filings and coverage.
• Collaborate with Lab Automation to integrate liquid handling with BLI workflows.
• Work with Data Science to translate sensorgrams into ML-ready datasets.
• Design automated biophysical screening assays (HT stability, solubility, self-association).
• Analyse high-throughput data and feed biophysical data into predictive models.
• QC analyse and troubleshoot developability experiments with R&D teams.
• Conduct self-directed research on binding profiles to inform engineering.
• Maintain thorough experimental records for cross-functional teams.

Skills

SPR/BLI expertise

Kinetics assay design

Data analysis

Antibody engineering knowledge

Education

PhD in protein/antibody engineering

MSc in related field (3–5 yrs)

Tools

Biacore/Sierra

Octet/Pioneer

HPLC/UPLC

DLS

Job description

LabGenius Therapeutics, based in London, seeks a kinetics expert to lead antibody binding characterization and to build a world-class platform from the ground up. You will drive high-resolution kinetic screening and hands-on development of Biacore/BLI workflows, feeding ML models with precise measurements.

You’ll own automated biophysical assays, stress-test binders for clinical readiness, and work with data science to translate sensor data into actionable insights for lead optimization.