Laboratory Technologist

BioLegend, Inc.; Macclesfield; On-site; GBP 42,000 - 64,000; Full time

Job summary

BioLegend, Inc. is seeking a technically skilled professional to perform high throughput clinical genome sequencing and related assays.

The role includes troubleshooting validation, reviewing lab results, and developing operational procedures while monitoring KPIs and quality metrics. Responsibilities also cover regulatory due diligence, internal auditing support, and timely reporting to the laboratory director.

Qualifications

• Clinical genomics experience with high throughput sequencing.
• Knowledge of clinical laboratory practices and quality systems.
• Experience in validation, testing and documentation in a regulated lab.
• Familiarity with ISO 15189 and UKAS is a plus.
• Able to write procedures and reports clearly.

Responsibilities

• Perform pre-analytical, analytical and post-analytical test processes and evaluate results.
• Engage in continuous process improvements and implement new services as needed.
• Adhere to quality control guidelines to ensure specimen integrity and result accuracy.
• Ensure work complies with country regulations and accreditation requirements.
• Assist in maintaining ISO 15189 and other regulatory standards.
• Perform laboratory assays and participate in shift work as required.

Skills

Clinical experience

Attention to detail

Communication skills

Regulatory knowledge

Quality control

Data interpretation

Education

HCPC registration (preferred)

Tools

Microsoft Word

Microsoft Excel

Outlook

Job description

Note this role is offered on a Fixed Term Contract (FTC) basis. Due to the location and shift patterns, having a car and drivers license is preferential.

Job Purpose:

Perform high throughput clinical genome sequencing and other clinical assays as needed. Assist in technical troubleshooting validation and testing processes, reviewing lab results, developing and writing operational procedures, monitoring laboratory key performance indicators, quality metrics and the QC program, timely reporting of quality event reporting to the laboratory director and to quality management, and provide regulatory, due diligence and internal auditing support

Duties and Responsibilities:

• Perform pre-analytical, analytical and post analytical test process and evaluate results produced relative to the diagnostic assessment
• Engage in continuous process and service improvement. Make and implement recommendations to improve operational efficiency and implement new services for areas of responsibility.
• Strictly adhere to quality control guidelines to ensure integrity of laboratory specimens and accuracy of results
• Ensure all work is in accordance with country regulations, organizational policies, and accreditation /compliance requirements
• Assist in maintaining ISO 15189 and other accreditation and regulatory agency standards and regulations
• Perform laboratory assays, including clinical and development testing, and other duties as required including shift work

Experience:

• Clinical experience with various molecular techniques including high throughput DNA Sequencing in a commercial, academic, or government laboratory
• HCPC registration preferred
• Experience with nucleic acid–based assays
• Must be detail oriented, highly organized, with excellent verbal and written communication skills.
• Practical experience with clinical laboratory practices and protocols is a definite plus.

Knowledge Skills and Abilities:

Language:

Ability to read and interpret documents such as safety rules, operating and maintenance instructions, and procedure manuals. Ability to write routine reports and correspondence.

Maths Ability:

Ability to work with mathematical concepts such as probability and statistical inference. Ability to apply concepts such as fractions, percentages, ratios, and proportions to practical situations. Reasoning Ability: Ability to define problems, collect data, establish facts, and draw valid conclusions. Ability to solve practical problems and deal with a variety of concrete variables in situations where only limited standardization exists. Ability to interpret a variety of instructions furnished in written, oral, diagram, or schedule form.

Computer Skills

To perform this job successfully, an individual should have knowledge of Microsoft Word, Outlook, and Microsoft Excel. Ability to operate laboratory computer systems

Other Skills:

Demonstrate effective interpersonal communications between departments and co-workers. Communicate effective (orally and written) with coworkers, employees of other departments, supervisors, and administration. Knowledge of quality control practices and requirements of UKAS, ISO 15189 CAP and other regulatory agencies

Working Conditions:

• Clinical Laboratory environment; exposure to blood borne pathogens, hazardous chemicals; must wear personal protective equipment including lab coat, gloves and completely closed footwear.
• Weekend rotation may be required