Influenza Immunology Research Associate

The Pirbright Institute; Woking; Presencial; GBP 40.000 - 50.000; Jornada completa

Ventajas ofrecidas por este puesto de trabajo

25 days annual leave

Generous pension scheme

Cycle to work scheme

Life assurance

On-site parking

Staff discount website

Descripción de la vacante

The Pirbright Institute is a world-leading research centre focused on viral diseases affecting livestock and their transmission to humans. This fixed-term role sits within the Mucosal Immunology Group, contributing to a transformative programme funded by major stakeholders and aligned with One Health aims.

The postholder will investigate mRNA-encoded antibodies and innate immune stimulators to prevent infection and interrupt transmission, applying diverse immunological techniques and

Formación

• Experience in influenza virological techniques including virus propagation and quantification.
• Experience in immunology including flow cytometry, analysis of cellular and humoral responses, ELISPOT, proliferation assays, ELISA, ADCC and ADCP
• Ability to effectively prioritise tasks and manage workload under pressure
• Willingness to work outside of standard working hours when required
• Experience of working in a laboratory environment
• Experience in biological containment practices and in working under biosecure conditions
• Experience in working with large animals
• Basic computer skills including use of Microsoft office packages, experience in data presentation and statistical analyses
• Evidence of experience and vision to carry out scientific research in a multi-disciplinary team

Responsabilidades

• Analysis of B and T cell responses following influenza infection.
• Identify and characterise antigen-specific B cells using flow cytometry.
• Contribute to antibody repertoire analysis under supervision.
• Cloning and recombinant expression of influenza specific monoclonal antibodies.
• Assist in functional testing of monoclonal antibodies, including ELISA, neutralisation, HAI, ADCC, CDC and ADCP assays.
• Preparation of virus challenge material and quantification of virus load in tissues.
• Assist with conducting influenza animal studies.
• Communicate progress and data in meetings and contribute to lab teamwork.

Conocimientos

Influenza virology

Virus propagation

Microneutralisation

Hemagglutination inhibition

Flow cytometry

ELISPOT

ELISA

ADCC

ADCP

Laboratory experience

Biosecurity

Herramientas

Microsoft Office

Descripción del empleo

The Pirbright Institute is a world-leading research centre focused on viral diseases affecting livestock and their transmission to humans. This fixed-term role sits within the Mucosal Immunology Group, contributing to a transformative programme funded by major stakeholders and aligned with One Health aims.

The postholder will investigate mRNA-encoded antibodies and innate immune stimulators to prevent infection and interrupt transmission, applying diverse immunological techniques and