In Vitro Profiling Scientist - Mechanistic Biology

AstraZeneca plc; Cambridge; On-site; GBP 32,000 - 46,000; Full time

Job summary

You will join AstraZeneca plc in Cambridge, UK, within the Discovery Sciences organisation. The role sits in Mechanistic Biology and Profiling, a laboratory-based team generating in vitro pharmacology, biochemistry, and cell biology data to support compound profiling and project progression across the early pipeline.

Working closely with colleagues across disciplines, you will design, execute and interpret experiments, applying scientific knowledge to deliver robust, reproducible data while

Qualifications

• Master’s degree or equivalent in a relevant scientific discipline such as cell biology, pharmacology, molecular biology or biochemistry.
• Hands-on experience in in vitro biology, cellular pharmacology or related laboratory-based experimental science.
• Experience with high-content imaging, plate-based cellular assays, and cell health assays.
• Ability to generate, analyse and interpret experimental data with emphasis on quality and reproducibility.
• Good communication skills and ability to work effectively in a collaborative, multidisciplinary team.
• Interest in applying digital and AI-enabled tools to support data analysis and workflow efficiency.

Responsibilities

• Generate in vitro profiling and mechanistic biology data to support project progression.
• Design and perform experiments using relevant cellular and biochemical approaches, with appropriate guidance depending on complexity.
• Analyse and interpret data and communicate conclusions clearly to project colleagues.
• Contribute to assay development, optimisation and troubleshooting to improve data quality and team delivery.
• Work effectively within cross-functional project teams, contributing experimental results and scientific insight.
• Apply quantitative, digital or AI-enabled tools to support data handling, image analysis, interpretation of complex datasets or workflow improvement.
• Maintain accurate records and clear documentation of experimental work.
• Keep up to date with relevant scientific and technical developments in mechanistic biology, profiling and related methods.

Skills

In vitro biology

Cellular pharmacology

High-content imaging

Biochemistry

Molecular biology

Data analysis

AI-enabled tools

Education

Master’s degree or equivalent in a relevant scientific discipline

Job description

You will join AstraZeneca plc in Cambridge, UK, within the Discovery Sciences organisation. The role sits in Mechanistic Biology and Profiling, a laboratory-based team generating in vitro pharmacology, biochemistry, and cell biology data to support compound profiling and project progression across the early pipeline.

Working closely with colleagues across disciplines, you will design, execute and interpret experiments, applying scientific knowledge to deliver robust, reproducible data while