Hybrid/Remote Principal Architect - Digital Pharma Manufacturing

GCS; United Kingdom; Hybrid; GBP 140,000 - 200,000; Full time

Job summary

GCS is seeking a Principal Architect to lead digital manufacturing architecture for a regulated pharmaceutical site. You will define strategy across manufacturing, labs, quality, automation, and IT to support GMP-compliant digital transformation.

You will govern architecture decisions, mentor teams, and partner with Site Leadership, Manufacturing, Engineering, Validation, and Cybersecurity to deliver scalable, compliant platforms.

Qualifications

• Significant experience in Enterprise Architecture within pharmaceutical/manufacturing environments.
• Strong knowledge of ERP, MES, LIMS, QMS, WMS, SCADA, DCS, PLCs.
• Experience with validation, CSV, data integrity, audit readiness.
• Experience with architecture roadmaps, standards, governance frameworks.

Responsibilities

• Define and own the site technology architecture strategy, standards, roadmaps, and target-state architectures.
• Lead architecture governance across IT, OT, automation, manufacturing, laboratory, quality, and enterprise systems.
• Drive IT/OT convergence and integration across ERP, MES, LIMS, QMS, WMS, SCADA, DCS, PLCs, historians, and equipment.

Skills

Enterprise Architecture

Solution Architecture

Manufacturing IT/OT Architecture

Digital Manufacturing

Regulated Environments

Job description

GCS is seeking a Principal Architect to lead digital manufacturing architecture for a regulated pharmaceutical site. You will define strategy across manufacturing, labs, quality, automation, and IT to support GMP-compliant digital transformation.

You will govern architecture decisions, mentor teams, and partner with Site Leadership, Manufacturing, Engineering, Validation, and Cybersecurity to deliver scalable, compliant platforms.