Head of Translational Bioinformatics Immunology - UK

UCB S.A.; Slough; On-site; GBP 80,000 - 100,000; Full time

Job summary

A global biopharmaceutical company is seeking a Translational Bioinformatics Leader in Slough, UK. This role involves leading a passionate team to generate insights from multi-omic profiling to support drug discovery in neurological diseases. The ideal candidate has a Ph.D., over 10 years of experience, and a passion for bioinformatics. Join us to create value and make your mark for patients.

Benefits

Career growth opportunities

Collaborative work environment

Supportive culture

Qualifications

• Ph.D. or equivalent with 10+ years of industry experience.
• Experience leading and mentoring teams of 5-10 scientists.
• Expertise in multi-omics data processing and analysis.

Responsibilities

• Lead a team to generate insights from patient samples.
• Define and execute the team's bioinformatics strategy.
• Collaborate with multidisciplinary scientists on drug discovery.

Skills

Leadership

Bioinformatics

Data analysis

Collaboration

Communication

Education

Ph.D. in Bioinformatics or related field

Tools

Docker

HPC

Job description

Overview

Make your mark for patients

We are looking for a talented and experienced Translational Bioinformatics Leader who is passionate and agile to join us in our Data Science and Analytics leadership team, based in Slough, UK.

About the role

In this role, you will lead a dynamic and highly motivated team of Bioinformatic scientists to generate actionable insights from multi-omic profiling of patient samples and in vitro / in vivo translational models, in partnership with the local biology focus areas. Participate in setting the function strategy, develop the team and progress state of the art in Bioinformatics in strict cooperation with other data science leaders.

By helping to better understand the pathways that drive disease, your work will directly support UCB’s Immunology research portfolio, spanning areas such as Inflammatory Dermatology, Senescence and Immune Reset.

Who you’ll work with

A key focus of the role is the close integration of team members into drug discovery project and platform teams, where they will collaborate with multidisciplinary scientists to design, execute, and interpret omic studies, driving the discovery and validation of therapeutic targets and translational research.

What you’ll do

• Leads and develops a bioinformatics function with strong ties with the local biology and translational functions
• Defines the team’s bioinformatics strategy and contribute significantly to both the DSA and the overall R&D digital strategy in collaboration with other digital leaders, working closely with other bioinformatics functions across Research.
• Provide scientific leadership, mentorship, and guidance to a team of bioinformatics scientists, fostering a collaborative and innovative work environment.
• Assist UCB’s therapeutic ambitions in neurological diseases by unlocking mechanistic insight from molecular profiling of patient samples, analysing perturbations of patient-derived cell systems and in vivo / ex vivodisease models, and enriching our knowledge of disease aetiology to inform new targets and drug mechanism of action.
• Maintain close relationships with focus areas and platform leads as well as with the overall research leadership, promoting team’s capabilities, identifying collaboration opportunities and expanding the overall impact of the team.
• Initiate (and participate in) collaborations with external parties, academic, commercial and industry consortia to expand access to human level data, develop state-of-the-art-defining methods, and provide novel insight, analysis and strategic steer
• Drive innovation in bioinformatics methods, data visualization, generative and predictive modelling to enhance the impact of data-driven research and help build the global bioinformatics tools and data infrastructure, in close collaboration with other Data Science functions.
• Provide authoritative scientific input in drug discovery projects and scientific governance meeting.
• Embed team members within therapeutic project teams to align bioinformatics efforts with project objectives. Foster clear communication of insights to influence project decision making and translational packages.

Interested? For this role we’re looking for the following education, experience and skills

• Ph.D. or equivalent in Bioinformatics, Computational Biology, Immunology, Genomics, or related field with 10+ years of industry experience.
• Proven ability to lead and mentor groups of 5-10 scientists, manage multiple priorities, and foster a collaborative work environment. Ideally in the context of pharmaceutical R&D.
• A passion for leveraging bioinformatics to accelerate drug discovery and understanding disease biology, with experience in Immunology insight delivering being a qualifying requirement.
• Expertise in multi-omics data processing, analysis, and interpretation, with a strong preference for single cell RNA-seq, spatial transcriptomics and methods for integrating genetic data to ID causal biology.
• Experience in supporting the translation of drug discovery projects into human clinical trials, enabling pre-clinical assessment, biomarker strategies and back translation.
• Exposure to multiple drug modalities including gene therapy would be a plus.
• Experience with HPC, cloud computing platforms, and containerisation technologies (e.g., Docker) for reproducible and portable bioinformatics workflows. Recent hands-on experience preferred.

Are you ready to ‘go beyond’ to create value and make your mark for patients? If this sounds like you, then we would love to hear from you!

About us

UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are around 8,500 people in all four corners of the globe, inspired by patients and driven by science.

Why work with us?

At UCB, we don’t just complete tasks, we create value. We aren’t afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected, and has equal opportunities to do their best work. We ‘go beyond’ to create value for our patients, and always with a human focus, whether that’s on our patients, our employees, or our planet. Working for us, you will discover a place where you can grow, and have the freedom to carve your own career path to achieve your full potential.

UCB is an equal opportunity employer. All employment decisions will be made without regard to any characteristic protected by applicable laws.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on [e-mail]. Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.