Epigenomics & CRISPR Research Technician

Newcastle University; Newcastle upon Tyne; Hybrid; GBP 30,000 - 32,000; Full time

Benefits offered by this job

Holiday package

LEAF award renewal

Health & wellbeing initiatives

Generous pension schemes

Job summary

Newcastle University is a global university where everyone is treated with dignity and respect. A Research Technician is needed to work on a Cancer Research UK funded project at the Wolfson Childhood Cancer Research Centre, applying CRISPR and epigenomic profiling to study super-enhancers in acute lymphoblastic leukaemia.

The post involves gene editing, sequencing-based analyses, and daily lab duties. Fixed-term, 3 years, 100% FTE; some flexibility for part-time work may be considered.

Qualifications

• BTEC HNC/HND or equivalent in a relevant subject or equivalent experience.
• Previous technical laboratory experience.
• Bachelor’s degree (or equivalent) in a relevant science subject – preferably biomedical.

Responsibilities

• Day-to-day management and support of experimental work involving patient-derived models of leukaemia
• Support epigenomic profiling techniques used by the wider team (initially under supervision)
• Support CRISPR gene editing approaches used by the group (initially under supervision)
• Keep accurate, secure, detailed records under guidance of research staff
• Provide specialist institute support for equipment maintenance, troubleshooting, SOPs and training
• Maintain laboratory stocks and order chemicals using the P2P system
• Ensure safe storage/handling of bio-chemicals and waste; update COSHH/BIOCOSHH forms
• Carry out additional duties as required by the Director or senior technical staff, including LEAF

Skills

Health & Safety

Teamwork

Independent work

Willingness to learn

Epigenomic profiling

CRISPR gene-editing

PCR

Cell culture

Nucleotide isolation

Education

BTEC HNC/HND or equivalent in relevant subject

Bachelor’s degree in relevant science (preferably biomedical)

Tools

CRISPR/Cas9 equipment

CUT&Tag prep

ATAC-seq setup

Job description

Newcastle University is a global university where everyone is treated with dignity and respect. A Research Technician is needed to work on a Cancer Research UK funded project at the Wolfson Childhood Cancer Research Centre, applying CRISPR and epigenomic profiling to study super-enhancers in acute lymphoblastic leukaemia.

The post involves gene editing, sequencing-based analyses, and daily lab duties. Fixed-term, 3 years, 100% FTE; some flexibility for part-time work may be considered.