CAR-T Clinical Fellow – Haematology

NHS; London; On-site; GBP 71,000; Full time

Job summary

An exciting opportunity within the malignant haematology department at UCLH focused on CAR-T therapy. The role offers structured training and the chance to engage in research, with responsibilities including patient management and coordination of clinical trials. This fixed-term position is ideal for a motivated doctor looking to develop their skills in a leading NHS trust.

Qualifications

• Medical degree and GMC registration required.
• Experience in teaching and clinical audit essential.
• Ability to work in a multidisciplinary team and prioritize workload.

Responsibilities

• Outpatient management of CAR-T therapy patients.
• Coordinate patient care with clinical trials team.
• Review patients in T-cell Immunotherapy clinics.

Skills

Teaching

Clinical audit

Interpersonal skills

Research methodology

Education

Medical degree

Membership of the Royal College of Physicians

Completed core medical training

Job description

Job summary

These roles are set within the department of malignant haematology at UCLH with a focus on cellular therapy (including CAR-T) in accordance with JACIE accreditation standards and NHSE guidance. The T-cell Immunotherapy service at UCLH is undergoing significant expansion and the post-holder will be involved in the delivery of (1) licenced/NHSE CAR T-cell products; (2) the academic and commercial CAR T-cell trial portfolio and (3) a portfolio of TCR-transduced T-cell and Tumour Infiltrating Lymphocyte (TIL) therapies for solid tumours which we hope to further cultivate and develop through the appointments.

There will be training in trial design and delivery through involvement in Tumour Management Group meetings for the academic trial portfolio alongside attendance at Site Initiation Visits for new studies. Training regarding the function of apheresis and the stem cell lab will also be provided.

The appointment will be initially for a period of 1 year from August 2025 with the potential for renewal on an annual basis. The roles will provide structured training in cellular therapy and it will be possible for applicants to develop a research project with a view to undertaking an MD/PhD. There will be an honorary contract with the UCL Cancer Institute for the post-holders.

Main duties of the job

Specific responsibilities will include:

• Outpatient management of patients receiving CAR-T therapy as well as providing support for patients with complications post-therapy
• Liaising with NCCP and clinical trials team to coordinate work-up and care of patients scheduled for CAR-T and other T-cell therapies therapy
• Liaising with district general hospitals to assist with cellular therapy patients
• Reviewing patients who attend on an emergency basis to the haematology day unit
• Reviewing patients in the weekly T-cell Immunotherapy clinics
• Interaction with lab teams processing translational patient samples and interface with academic trials manufacturing team.

About us

University College London Hospitals NHS Foundation Trust (UCLH) is one of the most complex NHS trusts in the UK, serving a large and diverse population. We provide academically led acute and specialist services, to people from the local area, from throughout the United Kingdom and overseas. Our vision is to deliver top-quality patient care, excellent education, and world-class research.

We provide first-class acute and specialist services across eight sites:

University College Hospital (incorporating the Elizabeth Garrett Anderson Wing)

National Hospital for Neurology and Neurosurgery

Royal National ENT and Eastman Dental Hospitals

University College Hospital Grafton Way Building

Royal London Hospital for Integrated Medicine

University College Hospital Macmillan Cancer Centre

The Hospital for Tropical Diseases

University College Hospital at Westmoreland Street

We are dedicated to the diagnosis and treatment of many complex illnesses. UCLH specialises in women's health and the treatment of cancer, infection, neurological, gastrointestinal and oral disease. It has world class support services including critical care, imaging, nuclear medicine and pathology.

We are committed to sustainability and have pledged to become a carbon net zero health service, embedding sustainable practice throughout UCLH. We have set an ambitious target of net zero for our direct emissions by 2031 and indirect emissions by 2040.

Details Date posted

21 May 2025

Pay scheme

Hospital medical and dental staff

Grade

Doctor - other

Salary

£70,425 a year Per annum plus London Weighting (See JD for out-of-hours)

Contract

Fixed term

Duration

12 months

Working pattern

Full-time

Reference number

309-UCLH-5824-A

Job locations

UCLH

235 Euston Road

London

NW1 2BU

Job description Job responsibilities

For the full Person Specification and more information regarding the main responsibilities of this role, please refer to the attached Job Description.

This vacancy may close before the current listed closing date. You are advised not to delay submitting your completed application.

Other potential training opportunitiesThere are many other training opportunities provided. The trainee will be encouraged, as a member of the Department, to participate in laboratory, clinical, teaching and research activities.

The duties outlined are not definitive and may be changed according to the needs of the service and training requirements. The post holder may be required to carry out other duties in occasional emergencies and unforeseen circumstances.

The post is subject to the Terms and Conditions of Service of Hospital Medical and Dental Staff (England & Wales), to the General Whitley Council Conditions of Service and also to the National Health Service Pension Regulations.

The applicant will take a full role in our out of hours on call rota. The appointee must hold at least MRCP Part I or equivalent. Registration with the General Medical Council is essential. Applicants are urged to have at least minimal cover with a medical defence organisation.

Come and be a part of the best NHS trust in England to work for, according to our staff*

UCLH top trust to work at in England for the second year running! : University College London Hospitals NHS Foundation Trust

*In the most recent NHS staff survey UCLH had the highest percentage of staff who said they would recommend us as a place to work, out of all general acute or acute/community NHS trusts in England for the second year in a row.

UCLH top trust to work at in England for the second year running! University College London Hospitals NHS Foundation Trust.

Once again, UCLH has received the highest score of all general acute and acute/community NHS trusts in England for staff that would recommend us as a place to work.

To discover more about what makes UCLH a great place to work, visit: Why Choose UCLH?

Job description Job responsibilities

For the full Person Specification and more information regarding the main responsibilities of this role, please refer to the attached Job Description.

This vacancy may close before the current listed closing date. You are advised not to delay submitting your completed application.

Other potential training opportunitiesThere are many other training opportunities provided. The trainee will be encouraged, as a member of the Department, to participate in laboratory, clinical, teaching and research activities.

The duties outlined are not definitive and may be changed according to the needs of the service and training requirements. The post holder may be required to carry out other duties in occasional emergencies and unforeseen circumstances.

The post is subject to the Terms and Conditions of Service of Hospital Medical and Dental Staff (England & Wales), to the General Whitley Council Conditions of Service and also to the National Health Service Pension Regulations.

The applicant will take a full role in our out of hours on call rota. The appointee must hold at least MRCP Part I or equivalent. Registration with the General Medical Council is essential. Applicants are urged to have at least minimal cover with a medical defence organisation.

Come and be a part of the best NHS trust in England to work for, according to our staff*

UCLH top trust to work at in England for the second year running! : University College London Hospitals NHS Foundation Trust

*In the most recent NHS staff survey UCLH had the highest percentage of staff who said they would recommend us as a place to work, out of all general acute or acute/community NHS trusts in England for the second year in a row.

UCLH top trust to work at in England for the second year running! University College London Hospitals NHS Foundation Trust.

Once again, UCLH has received the highest score of all general acute and acute/community NHS trusts in England for staff that would recommend us as a place to work.

To discover more about what makes UCLH a great place to work, visit: Why Choose UCLH?

Person Specification Knowledge and Qualifications Essential

• Medical degree
• Membership of the Royal College of Physicians or equivalent
• Eligible for full registration with the GMC and entry on the appropriate GMC Specialist Register at time of appointment and hold a current licence to practise.
• Completed core medial training or equivalent

Desirable

• Knowledge of the Clinical Governance framework of the NHS (including Research governance) and understanding of current changes in the organisation and management structures of the NHS. Ability to act within these parameters

Experience Essential

• Experience of teaching at undergraduate and postgraduate levels
• Clinical audit experience

Desirable

• Undergoing or completed higher specialist training in Haematology
• Experience in oncology
• Experience of laboratory research

Skills and Abilities Essential

• Ability and commitment to teach in a clinical setting
• Ability to organise and prioritise workload, to delegate responsibility as appropriate and to supervise staff
• Good inter-personal skills with an ability to work co-operatively in a multidisciplinary setting
• Ability to work effectively within a team environment & on own initiative
• Understanding of research methodology

Communication Essential

• Excellent communication skills/verbal and written. Good command of written and spoken English

Person Specification Knowledge and Qualifications Essential

• Medical degree
• Membership of the Royal College of Physicians or equivalent
• Eligible for full registration with the GMC and entry on the appropriate GMC Specialist Register at time of appointment and hold a current licence to practise.
• Completed core medial training or equivalent

Desirable

• Knowledge of the Clinical Governance framework of the NHS (including Research governance) and understanding of current changes in the organisation and management structures of the NHS. Ability to act within these parameters

Experience Essential

• Experience of teaching at undergraduate and postgraduate levels
• Clinical audit experience

Desirable

• Undergoing or completed higher specialist training in Haematology
• Experience in oncology
• Experience of laboratory research

Skills and Abilities Essential

• Ability and commitment to teach in a clinical setting
• Ability to organise and prioritise workload, to delegate responsibility as appropriate and to supervise staff
• Good inter-personal skills with an ability to work co-operatively in a multidisciplinary setting
• Ability to work effectively within a team environment & on own initiative
• Understanding of research methodology

Communication Essential

• Excellent communication skills/verbal and written. Good command of written and spoken English

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

UK Registration

Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).

Additional information Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

UK Registration

Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).

Employer details Employer name

University College London Hospitals NHS Foundation Trust

Address

UCLH

235 Euston Road

London

NW1 2BU

Employer's website

https://www.uclh.nhs.uk (Opens in a new tab)

Employer details Employer name

University College London Hospitals NHS Foundation Trust

Address

UCLH

235 Euston Road

London

NW1 2BU

Employer's website

https://www.uclh.nhs.uk (Opens in a new tab)