Research Associate- Pellegrini Group (Fixed Term)

TN United Kingdom; Cambridge; On-site; GBP 30,000 - 40,000; Full time

Job summary

A leading university in the UK is inviting applications for a Research Associate position in the Department of Biochemistry. The successful candidate will engage in cutting-edge research on DNA repair mechanisms, requiring expertise in biochemical techniques and protein engineering. This fixed-term role offers an exciting opportunity to contribute to significant scientific advancements.

Qualifications

• Experience in producing recombinant multi-protein assemblies via expression in insect or mammalian cells.
• Knowledge of quantitative biophysical techniques for characterizing macromolecular interactions is advantageous.

Responsibilities

• Work on biochemical reconstitution and structural characterization of protein complexes.
• Utilize advanced biophysical and structural techniques.

Skills

Biochemical reconstitution

Structural characterization

Protein engineering

Quantitative biophysical techniques

Education

PhD in Biochemistry or related field

Job description

Research Associate - Pellegrini Group (Fixed Term), Cambridge

Client: University of Cambridge

Location: Cambridge, United Kingdom

Job Category: Other

EU work permit required: Yes

Job Reference: 810d87547025

Job Views: 4

Posted: 23.05.2025

Expiry Date: 07.07.2025

Job Description:

Applications are invited for a Research Associate position in the laboratory of Professor Luca Pellegrini in the Department of Biochemistry at the University of Cambridge, UK.

The successful candidate will work on biochemical reconstitution and structural characterization of protein complexes important for Homology-Directed DNA Repair and genomic stability, referencing recent publications such as Appleby et al, Nat Comm, 2023 (doi: 10.1038/s41467-023-42830-1) and Hanthui YW et al, Mol Cell, 2024 (doi: 10.1016/j.molcel.2024.07.004).

This role involves a multidisciplinary approach, including preparative biochemistry of multi-protein complexes, protein engineering, and advanced biophysical and structural techniques. Experience in producing recombinant multi-protein assemblies via expression in insect or mammalian cells is required. Knowledge of quantitative biophysical techniques for characterizing macromolecular interactions is advantageous.

The University of Cambridge adheres to the San Francisco Declaration on Research Assessment (DORA), emphasizing research quality over publication metrics. Applicants should focus on research merits without including impact factors or uncontextualized metrics in their applications.

Funding is available from 01 December 2024, with a fixed-term contract until 31 May 2026.

For informal inquiries, please contact Professor Luca Pellegrini.

The university promotes equality, diversity, and inclusion and encourages applications from all societal sections. Applicants must be eligible to live and work in the UK.