Scientist - Multicellular Disease Models - 12 month contract

剥污瑩潮; London; On-site; GBP 60,000 - 85,000; Full time

Job summary

A leading biotech company in London seeks a Senior Scientist to develop multicellular disease models and support target validation. This role involves designing complex cellular models, analyzing data, and collaborating with interdisciplinary teams to advance healthcare innovations. Join a dynamic environment committed to scientific excellence and impactful research.

Qualifications

• 3-5 years of postdoctoral or industry experience in biotech, pharma, or academia.
• Proven track record in assay development and target validation.
• Expertise in developing mammalian cellular models.

Responsibilities

• Design and optimize 3D multicellular models for target biology studies.
• Contribute to mechanism of action studies using cellular and molecular biology techniques.
• Generate and analyze biological data for drug discovery projects.

Skills

Immunology

Cellular Biology

Molecular Biology

Data Analysis

Education

PhD in relevant field

Tools

CRISPR/Cas9

Flow Cytometry

RT-qPCR

Job description

Senior Scientist - Multicellular Disease Models – Target Validation

Join to apply for the Senior Scientist - Multicellular Disease Models – Target Validation role at Relation.

About Relation

Relation is an end-to-end biotech developing transformational medicines, with technology at our core. Our ambition is to understand human biology in unprecedented ways, discovering therapies to treat some of life’s most devastating diseases. We leverage single-cell multi-omics directly from patient tissue, functional assays, and machine learning to drive disease understanding, from cause to cure.

We are rapidly scaling our technology and discovery teams, offering a unique opportunity to join one of the most innovative biotech companies. Our state-of-the-art laboratories in London foster interdisciplinarity and turn groundbreaking ideas into positive impacts for patients.

We are committed to diversity and inclusion, and as an equal opportunities employer, we do not discriminate based on gender, ethnicity, or other protected characteristics. Join us to be part of a talented team that advances drug discovery and impacts patient lives.

Opportunity

We seek a Senior Scientist in Multicellular Disease Models to develop disease-relevant multicellular models with multi-parametric endpoints, support target validation experiments, analyze scientific data, and maintain laboratory operations. You will contribute to research and project success, collaborating with wet-lab scientists and data scientists, and helping shape our organizational culture.

Your Responsibilities

1. Design, optimize, and establish 3D multicellular and complex cellular models mimicking human tissue and disease states for target biology interrogation.
2. Contribute to mechanism of action studies using cellular and molecular biology techniques.
3. Utilize cellular and molecular biology expertise to advance projects on novel target biology.
4. Generate and analyze biological data for drug discovery projects.
5. Ensure efficient lab operations and contribute to team responsibilities.

Professionally, you have

• A PhD plus 3-5 years of experience in biotech, pharma, or academia, with a strong record in assay development and target validation.
• Expertise in immunology, evidenced by publications.
• Experience with mammalian cellular models, including 2D and 3D assays, with disease-relevant endpoints.
• Proficiency with multi-parameter endpoints such as flow cytometry, microscopy, and RT-qPCR.
• Knowledge of gene editing tools (e.g., CRISPR/Cas9) and RNA interference.
• Ability to work collaboratively and present findings effectively.

Desirable Knowledge or Experience

• Previous experience in pharma or biotech environments.
• Familiarity with electronic lab notebooks and SOPs.

Personal Attributes

• Collaborative team player.
• Effective communicator.
• Driven by preclinical impact.
• Motivated to stay at the forefront of science.
• Passionate about healthcare advancements.

Join us in this exciting role to impact genetics, disease risk, and deliver transformative medicines. Together, we set new standards in machine learning and genetics. The patient awaits!