Downstream Processing Senior Scientist

WISE Campaign; Stevenage; Hybrid; GBP 40,000 - 80,000; Full time

Job summary

An established industry player is seeking a passionate Downstream Processing Senior Scientist to join their innovative team in Stevenage. This role is pivotal in shaping the future of oligonucleotide development and involves working on cutting-edge purification processes. You will collaborate with various stakeholders to enhance bioprocessing techniques and contribute to the development of robust purification platforms. If you are driven by scientific excellence and eager to make a significant impact in the biopharmaceutical field, this opportunity is perfect for you. Join a forward-thinking company that values growth, safety, and inclusion, and be part of a team that is committed to advancing healthcare solutions.

Benefits

Competitive salary

Annual bonus based on company performance

Healthcare and wellbeing programmes

Pension plan membership

Shares and savings programme

Qualifications

• Extensive experience in bioprocessing with focus on chromatography and ultrafiltration.
• Proven experience in Biologics/Oligonucleotides and/or Biomanufacturing.

Responsibilities

• Support development of downstream purification processes for oligonucleotide products.
• Author technical reports and engage with manufacturing teams for successful campaigns.

Skills

Bioprocessing

Chromatography

Ultrafiltration

Oligonucleotide development

Technical report writing

Education

MSc or Bachelor's degree in Biochemistry

PhD in related discipline

Tools

Quality by Design (QbD) principles

Job description

근무지: UK - Hertfordshire - Stevenage
포스팅 날짜: Apr 24 2025

We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.

We embrace modern work practises; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work.

Discover more about our company wide benefits and life at GSK on our webpage Life at GSK | GSK

Downstream Processing Senior Scientist

We are seeking an experienced and passionate Downstream Processing Senior Scientist to join our Enzyme and Oligonucleotide Development group in Stevenage, UK.

This is an exciting opportunity to be at the forefront of an exciting and growing area, shaping the future direction of innovative medicines and playing a key role in developing our scientific approach to Oligonucleotide development and manufacture.

The successful candidate will have extensive experience in bioprocessing and be an expert in key bioprocessing unit operations, with a focus on chromatography and ultrafiltration. They will help develop downstream purification processes for our oligonucleotide products, working closely with key stakeholders in partner groups such as analytical, process engineering and clinical and commercial manufacturing. They will also play a key role in the development of our oligonucleotide purification platform, collaborating internally and externally to explore cutting-edge scientific approaches and technologies.

In this role you will…

• Support the development of robust downstream purification processes for oligonucleotide products, both in early and late-stage development, working with members of the process development team.
• Author/contribute to detailed technical reports and process transfer documents to support tech transfer activities, and engage with manufacturing teams to ensure successful campaign completion.
• Stay current with the latest downstream technology improvements and process development approaches, leading continuous improvement efforts to maintain GSK's technical competitiveness and play a key role in platform development.
• Contribute to project and matrix teams to deliver both the GSK portfolio and technology development objectives

Basic Qualifications/Experience:

We are looking for professionals with these required skills to achieve our goals:

• MSc or Bachelor's degree in Biochemistry, Biotechnology, Biochemical/Chemical Engineering, or a related discipline
• Proven academic or Industrial experience in Biologics/Oligonucleotides and/or Biomanufacturing

Preferred Qualifications/Experience:

If you have the following characteristics, it would be a plus:

• PhD in a related discipline and/or relevant industrial experience, and experience of helping develop purification processes for Oligonucleotides
• An understanding of oligonucleotide chemistry, structure, and properties to inform purification process design
• Knowledge of Quality by Design (QbD) principles and their application to downstream process development

Closing Date for Applications – Thursday 8th May 2025

Please take a copy of the Job Description, as this will not be available post closure of the advert.
When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.