Director, Legal - UK

Major, Lindsey & Africa, LLC; Greater London; On-site; GBP 140,000 - 210,000; Full time

Job summary

Revolution Medicines is seeking a high-impact UK Legal Lead to partner with the UK General Manager and leadership on commercial strategy, regulatory compliance, and market access. You will counsel across Sales, Marketing, Medical Affairs, Finance and Government Affairs, overseeing UK disputes and coordinating with external counsel.

The role requires 8–12 years in life sciences, J.D. or equivalent, and fluency in English. Travel within UK and internationally is expected.

Qualifications

• 8–12 years of legal experience in life sciences
• In-house or law firm experience supporting life sciences
• Strong knowledge of UK pharmaceutical law and commercial issues
• Experience advising commercial pharmaceutical organisations
• Experience supporting market access, reimbursement or healthcare contracting

Responsibilities

• Serve as the primary legal advisor to the UK General Manager and Leadership Team.
• Provide practical, solution-oriented legal advice to support commercial decisions.
• Lead legal support for UK commercialization of oncology portfolio.
• Review and negotiate commercial agreements for UK operations.
• Coordinate with external counsel on complex disputes and regulatory matters.
• Develop litigation strategies and manage litigation budgets.

Skills

Strategic partnership

Negotiation

Stakeholder management

Regulatory acumen

Communication

Risk assessment

Cross-functional collaboration

English fluency

Education

J.D. or equivalent

Admission in US/UK/EU jurisdiction

Job description

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

Key Responsibilities:

Strategic Business Partner

• Serve as the primary legal advisor to the UK General Manager and local Leadership Team.
• Provide practical, solution-oriented legal advice to support commercial decision-making and business strategy.
• Participate as a trusted member of the UK leadership team, proactively identifying legal risks and opportunities.
• Support the successful launch and ongoing commercialisation of the Company's oncology portfolio in UK.

Commercial & In-Market Legal Advice

• Advise on all legal aspects of commercial operations within UK.
• Support Sales, Marketing, Medical Affairs, Market Access, Government Affairs, Regulatory Affairs and Finance.
• Provide legal guidance on promotional activities, field-based engagements, digital initiatives, early access and patient support programs.
• Review and negotiate commercial agreements supporting the UK business.

Market Access & Pricing

• Lead legal support for market access and reimbursement initiatives.
• Draft and negotiate rebate agreements, market access agreements and value-based arrangements with statutory and private healthcare stakeholders.
• Advise on pricing, reimbursement, tender participation and healthcare contracting.
• Partner with Market Access and Government Affairs to assess legal implications of evolving reimbursement policies.

Business Partner Relationships

• Support strategic relationships with healthcare institutions, research organisations, commercial partners and service providers.
• Draft and negotiate agreements with consultants, vendors, commercial service providers and other business partners.
• Advise on governance of strategic collaborations and alliance relationships.
• Support third-party due diligence and ongoing relationship management.
• Advise on UK and European competition law issues affecting pharmaceutical commercialisation.
• Counsel business teams on pricing, distribution, information exchanges, collaborations, tenders and interactions with competitors.
• Provide legal guidance regarding healthcare professional engagements, transfers of value, sponsorships, grants and interactions with healthcare organisations.
• Partner closely with Compliance to ensure adherence to applicable pharmaceutical industry codes and internal policies.
• Manage actual and threatened litigation involving the UK affiliate.
• Coordinate with external counsel on commercial disputes, regulatory matters, employment-related legal issues (working alongside Employment Counsel), product-related claims and investigations.
• Develop litigation strategy in collaboration with the VP Legal, Europe and senior management.
• Manage legal holds, investigations and dispute resolution processes.

Regulatory & Local Legal Support

• Advise on UK legal requirements impacting commercial operations.
• Support implementation of new legislation affecting pharmaceutical companies.
• Provide legal guidance on consumer protection, unfair competition, advertising, procurement and commercial regulations.
• Coordinate with specialist external counsel on complex local law matters where appropriate.

Cross-Functional Collaboration

• Partner with Global Legal, Compliance, Regulatory Affairs, Medical Affairs, Quality, Supply Chain, Finance and Human Resources.
• Support internal investigations, audits and compliance initiatives.
• Develop and deliver legal training to the UK affiliate.
• Contribute to the development of legal policies, templates and best practices across the European legal function.

Outside Counsel Management

• Select, instruct and manage UK external counsel.
• Oversee litigation budgets and legal spend.
• Ensure efficient delivery of high-quality legal services while controlling costs.

Qualifications:

Required

• J.D. (or equivalent law degree) and admission to practice in at least one U.S. state or a UK or European jurisdiction.
• 8–12 years of legal experience, including significant in-house or law firm experience supporting the life sciences industry.
• Strong knowledge of UK pharmaceutical law and commercial legal issues.
• Experience advising commercial pharmaceutical organisations.
• Experience supporting market access, reimbursement or healthcare contracting.
• Familiarity with competition law, healthcare compliance and pharmaceutical promotional regulations.
• Demonstrated ability to advise senior business leaders in a highly regulated environment.
• Excellent negotiation, communication and stakeholder management skills.

Preferred

• Experience supporting oncology or specialty pharmaceutical products.
• In-house legal experience supporting a UK pharmaceutical affiliate.
• Experience supporting a first commercial launch.
• Familiarity with UK statutory health insurance (GKV) contracting and reimbursement frameworks.
• Experience managing commercial litigation and regulatory investigations.
• Fluency in English.

Core Competencies

• Strategic business partnership
• Commercial judgment
• Executive presence and influencing skills
• Competition law expertise
• Healthcare regulatory knowledge
• Negotiation and contracting
• Litigation management
• Cross-functional collaboration
• Pragmatic risk management
• Strong project leadership

Travel

Approximately 10–20% travel within UK and internationally, including periodic travel to the Company's U.S. and European headquarters and European offices.

Why Join Us

This is a unique opportunity to serve as the lead legal advisor for one of the Company's most important commercial markets during a transformational period. As the Company launches its first oncology therapy in Europe, you will play a central role in shaping legal strategy, partnering directly with the UK General Manager and executive leadership, and helping build a high-performing commercial organisation that delivers innovative medicines to patients.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, colour, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.