Director Clinical Development

Morgan Prestwich - Life Science & Healthcare Executive Search; Greater London; Hybrid; GBP 110,000 - 170,000; Full time

Job summary

Morgan Prestwich - Life Science & Healthcare Executive Search is seeking a Clinical Study Physician to lead a global Phase 3 programme in a hybrid role based in London. The position blends hands-on operational delivery with strategic input across CROs, sites and cross-functional teams.

The right candidate will be an MD with 5+ years in clinical development, strong regulatory knowledge and proven global trial delivery. This is a senior, fast-paced role in a biotech environment.

Qualifications

• Medical Doctor with 5+ years of clinical development experience.
• Experience delivering global trials across multiple phases, ideally including Phase 3.
• Strong knowledge of ICH-GCP, FDA, EMA and global trial regulations.
• Experience managing CROs and external vendors.
• Strong project management, communication and organisational skills.
• Hands-on, fast-paced and evolving environment with strategic and detailed work.
• Biotech/start-up experience and/or rare disease exposure is desirable.

Responsibilities

• Provide hands-on clinical and operational leadership across the Phase 3 programme.
• Contribute to the Clinical Development Plan and wider programme strategy.
• Collaborate with investigators, KOLs and clinical sites through study planning, conduct and reporting.
• Oversee CROs, vendors, timelines, milestones, budgets and study delivery.
• Support protocol, ICF, CRF, monitoring plans and clinical study report development and review.
• Identify operational risks and ensure quality, regulatory compliance and on-time delivery.
• Partner with Clinical Development, Regulatory, Pharmacovigilance, Biostatistics and Data Management.
• Support inspection readiness, audits and regulatory interactions.
• Build and mentor clinical operations colleagues and foster a high-performance culture.

Skills

Clinical development

CRO management

Project management

Regulatory knowledge

Education

Medical Doctor

Job description

Clinical Study Physician | Phase 3 | Biotech | Hybrid – London

We are looking for an experienced Clinical Study Physician to join a growing clinical development team and play a key role in the delivery of a global Phase 3 clinical programme.

Hybrid working – a mix of home-based and 3 days office-based working in London

This is a hands-on role for a medically qualified clinical development professional who enjoys being close to the science, the sites and the day-to-day execution of clinical trials. You will combine strategic input with active operational involvement, working closely with CROs, investigators, sites and cross-functional teams to deliver the programme successfully.

Key responsibilities

• Provide hands-on clinical and operational leadership across the Phase 3 programme.
• Contribute to the Clinical Development Plan and wider programme strategy.
• Work closely with investigators, KOLs and clinical sites throughout study planning, conduct and reporting.
• Oversee CROs, vendors, timelines, milestones, budgets and study delivery.
• Support the development and review of protocols, ICFs, CRFs, monitoring plans and clinical study reports.
• Identify and manage operational risks, ensuring quality, compliance and delivery against timelines.
• Partner closely with Clinical Development, Regulatory, Pharmacovigilance, Biostatistics and Data Management.
• Support inspection readiness, audits and regulatory interactions.
• Build and mentor clinical operations colleagues and foster a collaborative, high-performance culture.

About you

• Medical Doctor with 5+ years' clinical development experience within biotech, pharma or CRO environments.
• Proven experience delivering global clinical trials across multiple phases, ideally including Phase 3.
• Strong knowledge of ICH-GCP, FDA, EMA and global clinical trial regulations.
• Experience managing CROs and external vendors.
• Strong project management, communication and organisational skills.
• Comfortable working in a hands-on, fast-paced and evolving environment, with the ability to operate both strategically and in the detail.
• Experience in a biotech/start-up environment and/or rare disease is highly desirable.

This is an opportunity to make a real impact on a late-stage clinical programme while remaining close to the execution and the patient.

If you're a medically qualified clinical development professional who enjoys rolling up your sleeves and getting things done, we'd love to hear from you.