Clinical Research Physician

EPM Scientific; Greater London; On-site; GBP 90,000 - 130,000; Full time

Job summary

EPM Scientific is seeking experienced physicians to join its clinical development team in the UK, offering Sub-Investigator (Sub-PI) or Principal Investigator (PI) roles across multiple therapeutic areas and trial phases.

These positions focus on high-quality patient safety, regulatory compliance, and data integrity, with opportunities to lead site activities, mentor study staff, and collaborate with sponsors and CRO partners in a fast-paced, global environment.

Qualifications

• Medical degree and GMC registration with fitness to practice.
• Experience in clinical trials across phases I–IV preferred.
• Experience as Sub-Investigator or PI highly desirable.

Responsibilities

• Conduct and oversee clinical trial activities in accordance with GCP, protocol requirements, and regulatory standards.
• Perform medical assessments, physical examinations, and safety evaluations of study participants.
• Support participant recruitment, screening, enrollment, and ongoing trial management.
• Review safety information, adverse events, and clinical data throughout study conduct.
• Collaborate closely with clinical operations, sponsors, research nurses, and site staff.
• Contribute to investigator meetings, protocol training, and study-related documentation.
• Ensure high standards of participant safety, data integrity, and regulatory compliance.

Skills

Clinical Research

Clinical Trials

GCP

Stakeholder Management

Multidisciplinary Collaboration

Communication Skills

Education

Medical degree (MBBS/MBChB/MD) or equivalent

GMC Registration

Job description

A leading global clinical research organization is seeking experienced physicians to join its growing clinical development team in the UK. This position offers the opportunity to play a key role in the delivery of clinical trials, either as a Sub-Investigator (Sub-PI) or Principal Investigator (PI), supporting studies across a variety of therapeutic areas and phases of development.

This is an excellent opportunity for physicians who are passionate about clinical research and wish to further develop their expertise within a highly collaborative, patient-focused environment.

Key Responsibilities

• Conduct and oversee clinical trial activities in accordance with GCP, protocol requirements, and regulatory standards.
• Perform medical assessments, physical examinations, and safety evaluations of study participants.
• Support participant recruitment, screening, enrollment, and ongoing trial management.
• Review safety information, adverse events, and clinical data throughout study conduct.
• Collaborate closely with clinical operations, sponsors, research nurses, and site staff.
• Contribute to investigator meetings, protocol training, and study-related documentation.
• Ensure high standards of participant safety, data integrity, and regulatory compliance.

Requirements

• Medical degree (MBBS, MBChB, MD, or equivalent) with current GMC registration.
• Previous experience working within clinical trials, either in an investigator site, CRO, pharmaceutical, or academic research setting.
• Experience acting as a Sub-Investigator, Principal Investigator, or Study Physician is highly desirable.
• Strong understanding of ICH-GCP and clinical research regulations.
• Excellent communication and stakeholder management skills.
• Ability to work effectively within a multidisciplinary environment.

Desirable Experience

• Experience across Phase I-IV clinical trials.
• Exposure to industry-sponsored studies.
• Background in therapeutic areas such as oncology, immunology, infectious diseases, cardiovascular, metabolic disorders, neuroscience, or rare diseases.

Desired Skills and Experience

• Medical Degree (MBBS, MD, MBChB or equivalent)
• GMC Registration
• Clinical Research
• Clinical Trials (Phase I-IV)
• Principal Investigator (PI)
• Sub-Investigator (Sub-PI)
• Study Physician
• ICH-GCP
• Patient Safety
• Clinical Development
• Adverse Event Reporting
• Protocol Compliance
• Clinical Assessments
• Drug Development
• Medical Monitoring
• Regulatory Compliance
• Investigator Site Management
• Electronic Data Capture (EDC)
• Stakeholder Management
• Life Sciences Research