Computational Research Associate, Structural Cell Biology

Instruct-ERIC; United Kingdom; Remote; GBP 35,000 - 52,000; Full time

Job summary

The Rosalind Franklin Institute in the United Kingdom is seeking a Research Associate in Structural Cell Biology to drive computational reconstruction of macromolecular structures from in-situ data, with a focus on cytoskeletal and mitochondrial changes during aging and disease.

You will collaborate with Imperial, University College London and the University of Oxford to coordinate specimen procurement, acquire high-quality cryo-electron tomography data, and develop structure-determination

Responsibilities

• Develop and streamline computational approaches to in-situ structure determination methods from tissue sources that enable an assessment of macromolecular diversity.
• Demonstrate leadership as part of a team working with clinicians to prepare tissues for cryo-electron tomography.
• Plan and conduct experiments, analyse and interpret results and supervised delivery of outputs (e.g. research reports, patent applications) in a scientific/technology area of interest.
• Work within a project team, contributing to wider projects around key Franklin's Challenges.
• Lead major contributions to research outputs including papers, patents and both internal and external presentations.
• Support and develop others including day-to-day supervision of students or visitors in areas related to your own research.
• Have supervised, staged progression to first stages of scientific independence with opportunities to further develop science and skills/experience.
• Enhance your research through collaboration with other researchers and make active contributions to exchange of ideas through your own network.
• Be able to understand, interpret, create and communicate appropriately within a research context.
• Develop search and discovery skills and techniques.
• Be supervised by a Scientist/Senior Scientist in delivery of research outputs, either in the context of a project or Franklin's Challenge or as an early career development fellow.

Job description

The Rosalind Franklin Institute in the United Kingdom is seeking a Research Associate in Structural Cell Biology to drive computational reconstruction of macromolecular structures from in-situ data, with a focus on cytoskeletal and mitochondrial changes during aging and disease.

You will collaborate with Imperial, University College London and the University of Oxford to coordinate specimen procurement, acquire high-quality cryo-electron tomography data, and develop structure-determination