Clinical Research Associate: Site Monitoring Oversight

Parexel; Dover; Hybrid; GBP 35,000 - 56,000; Full time

Job summary

Parexel is seeking a Clinical Research Associate (CRA) to manage investigator sites throughout the lifecycle of assigned clinical trials. You will monitor, support site activation, ongoing study conduct, and close-out while safeguarding patient safety and data integrity.

You will collaborate with the Site Care Partner and study team to ensure protocol compliance, site performance and timely delivery of study milestones. Travel will be substantial, with remote monitoring as needed.

Qualifications

• 2+ years of site monitoring experience in clinical research.
• Fluent English and local language(s) of the work country.
• Willingness and ability to travel 60–80%.
• Hold a valid driver’s license and passport.

Responsibilities

• Ensure proper conduct of clinical trials per SMP, laws, GCP and Sponsor standards.
• Manage operational aspects for site activation through database lock.
• Serve as primary contact for investigator sites and collaborate with SCP.
• Facilitate information flow among study team, vendors and sites.
• Coach and train site staff to ensure protocol compliance and patient safety.
• Attend investigator meetings and support site activation and recruitment.
• Conduct onsite or remote monitoring and close-out activities per SMP and SOPs.
• Monitor adverse events and collaborate with Drug Safety Unit to resolve SAE reports.
• Submit required TMF and site documentation within timelines.
• Identify and resolve investigator site issues and implement CAPA measures.
• Ensure oversight of investigational product at sites (receipt, storage, destruction).
• Support database release as needed.

Skills

Clinical trials

ICH/GCP

FDA regulations

English fluency

Travel readiness

Driver license

Education

Bachelor's in life sciences

Job description

Parexel is seeking a Clinical Research Associate (CRA) to manage investigator sites throughout the lifecycle of assigned clinical trials. You will monitor, support site activation, ongoing study conduct, and close-out while safeguarding patient safety and data integrity.

You will collaborate with the Site Care Partner and study team to ensure protocol compliance, site performance and timely delivery of study milestones. Travel will be substantial, with remote monitoring as needed.