Clinical Data Manager

Cancer Research UK (CRUK); Stratford-upon-Avon; Hybrid; GBP 39,000 - 44,000; Full time

Job summary

Cancer Research UK is seeking a Clinical Data Manager to join the Centre for Drug Development on a 24-month fixed term contract. You will lead data management for DETERMINE, our multi-drug precision medicine platform trial in oncology, coordinating data quality and eCRF review across arms.

You will work in a small team of 8 data management professionals, collaborating with clinical operations and statisticians to ensure timely, accurate data for early phase trials.

Qualifications

• Biomedical science graduate or nursing qualification or equivalent.
• Experience in clinical data management and drug development.
• Experience using an electronic data capture (EDC) database.
• Excellent written and verbal communication.
• Excellent attention to detail with big-picture focus.
• Strong planning and organisational skills to meet timelines.
• Desirable: experience on oncology trials.

Responsibilities

• Lead data management of assigned arms of the DETERMINE trial.
• Review trial data to ensure data quality and address issues.
• Develop or amend clinical trial databases and specify edit checks.
• Facilitate reporting by validating data listings and tables.
• Monitor data entry and cleaning; lock data to protect integrity.
• Work to achieve KPIs and project goals.

Skills

Data management

Communication

Attention to detail

Planning & organisation

Oncology trials

Education

Biomedical science degree

Nursing qualification

Tools

EDC clinical trial database

Job description

Transformative methods. Inquisitive minds. Life-changing foresight.

Transformative methods. Inquisitive minds. Life-changing foresight.

Clinical Data Manager

£39,000 – £44,000 plus benefits

Reports to: Data Management Operations Manager

Directorate: Research & Innovation

Contract: 24-month Fixed Term Contract

Hours: Full time, 35 hours per week or a 4 day week of 28 hours.

Location: Stratford, London (high flex 1-2 days per week) or home based, UK (at request).

Closing date: Sunday 30th August 23:55pm

Interview date: Approximately w/c 14th September

Recruitment process: Competency based interview via Microsoft Teams + Data Management Task

Visa sponsorship: You must be eligible to work in the UK to apply for this vacancy. Cancer Research UK is not able to offer visa sponsorship.

About us: At Cancer Research UK, we exist to beat cancer. Cancer Research UK (CRUK) are looking for a Clinical Data Manager to join our team within our Centre for Drug Development (CDD) on a 24 month fixed term contract. CDD is the sponsor of early phase and precision medicine clinical trials in oncology agents. Our broad portfolio rivals that of a medium‑sized pharmaceutical company, spanning antibodies, cell therapies, vaccines, drug conjugates and small molecules, making this an interesting and dynamic area to work in. It is an exciting time for CDD as we’re expanding our teams to move forward with an ambitious new strategy to maximise the impact of our research to benefit patients. Several teams are hiring new roles to make this new strategy a reality, expanding the size of our project portfolio and bringing in new skills as we work more internationally.

This is a great opportunity for an experienced Clinical Data Manager, with a keen interest in the field of Oncology, to join a small team made up of 8 Data Management professionals. This will allow you to work on DETERMINE, our multi‑drug, precision medicine platform trial in rare cancers, recruiting both adults and children.

What will I be doing?

• Lead the data management of assigned arms of the DETERMINE trial.
• Review the clinical trial data ensuring that data cleaning is managed effectively and efficiently, highlighting any issues that may affect data quality.
• Manage the development or amendment of clinical trial databases, reviewing eCRFs, specifying edit checks and performing validation.
• Facilitate the reporting of the data by managing the specification and validation of data listings and tables, coding adverse event terms and reconciling serious adverse events.
• Monitor the status of data entry and data cleaning, locking data when appropriate to protect data integrity.
• Work to achieve key performance indicators and project goals.

What are we looking for?

• You will be a biomedical science graduate, hold a nursing qualification or have equivalent relevant experience.
• Proven knowledge and understanding of clinical data management and drug development, working to ICH/GCP and relevant legislation.
• Good knowledge and previous use of an electronic data capture (EDC) clinical trial database.
• Excellent written and verbal communication skills.
• Excellent attention to detail whilst retaining sight of the bigger picture.
• Good planning and organisational skills, able to prioritise and manage multiple competing tasks whilst working to challenging timelines.
• In addition, experience of working on oncology trials would be desirable.

Our organisation values are designed to guide all that we do.

Bold: Act with ambition, courage and determination

Credible: Act with rigour and professionalism

Human: Act to have a positive impact on people

Together: Act inclusively and collaboratively

We’re looking for people who can believe in and embody these organisation values and can use them to drive forward progress against our mission to beat cancer.

What will I gain?

We create a working environment that supports your wellbeing and provide a generous benefits package, a wide range of career and personal development opportunities and high-quality tools. Our policies and processes enable you to improve your work‑life balance, take positive steps in your career and achieve your personal wellbeing goals.

You can explore our benefits by visiting our careers web page.

We want to see every candidate performing at their best throughout the job application process, interview process and whilst at work. We therefore ask you to inform us of any concerns you have or any adjustments you might need to enable this to happen.

Unfortunately, we are unable to recruit anyone below the age of 18, so that we can protect young people from health & safety and safeguarding risks.