Cheminformatics Researcher

Talentmark; Bracknell; Hybrid; GBP 55,000 - 69,000; Full time

Job summary

Talentmark are recruiting a Cheminformatics Researcher to join a leading pharmaceutical company on a 12-month contract. The role is hybrid with a minimum of 2 days per week in the Bracknell office.

You will apply computer-based chemistry methods and AI/ML to explore and design lipid molecules used in targeted lipid nanoparticles. You will help build and improve a virtual library of lipid designs, perform data analysis, and collaborate with scientists to develop predictive models and robust

Qualifications

• PhD in Cheminformatics, Computational Chemistry, or related field.
• Experience designing chemical libraries and analysing structure-activity relationships.
• Strong data analysis and AI/ML experience; basic statistics knowledge.
• Strong Python programming and data visualization skills.
• Understanding of lipid nanoparticle formulation is helpful but not required.

Responsibilities

• Represent lipid molecules digitally and build tools to analyse lipid structures.
• Design new lipid structures using available building blocks, finding useful patterns.
• Build and improve a virtual lipid library using data analysis and AI/ML.
• Build and test models predicting how lipid structure affects performance.
• Create processes to prioritise lipids balancing variety with lab capacity.
• Maintain high-quality data analysis and collaborate with scientists across the team.

Skills

Python

Data analysis

AI/ML

Statistics

Data visualization

Education

PhD in Cheminformatics, Computational Chemistry, or related field

Tools

Cheminformatics tools

Python scripting

Job description

Talentmark are recruiting for a Cheminformatics Researcher to join a company in the pharmaceutical industry on a contract basis for 12 months. This role is hybrid, with a minimum of 2 days per week in the Bracknell office.

Company:

Our client is one of the largest pharmaceutical companies in the world. They focus on finding answers for some of the world's most urgent medical needs.

Salary:

£39.84 - £49.12 per hour PAYE

Cheminformatics Researcher Role:

We're looking for a junior cheminformatics scientist to join a Genetic Medicine team. You'll use computer-based chemistry methods and AI/machine learning to help explore and design lipid molecules used in targeted lipid nanoparticles (a type of drug-delivery particle). You'll help build and improve a library of lipid designs, combining data analysis, scientific know-how, and computer modelling.

Your Responsibilities:

• Help figure out the best ways to represent lipid molecules digitally, and build tools to analyse and sort lipid structures from internal and public data.
• Design new lipid structures using available chemical building blocks, looking for patterns that affect how well they work.
• Help build and improve a virtual library of lipid designs, using data analysis, AI/ML tools, and chemical know-how.
• Build and test models that predict how a lipid's structure affects its real-world performance.
• Create processes to select and prioritise which lipids should be made, balancing variety with practical limits like lab capacity.
• Keep data analysis consistent and high quality, and work closely with other scientists across the team.

Your Background:

• A PhD in Cheminformatics, Computational Chemistry, or a related field; relevant work or research experience is a plus.
• Experience using cheminformatics methods to design chemical libraries and analyse structure-activity relationships.
• Solid experience with data analysis and AI/machine learning, plus a good understanding of basic statistics; experience with small molecules or lipids is a bonus.
• Strong programming skills, especially in Python, and experience creating data visualisations.
• Some understanding of lipid nanoparticle formulation is helpful, but not essential.
• Comfortable learning new cheminformatics tools and software as needed.

It is essential that applicants hold entitlement to work in the UK.

This role may be subject to a satisfactory basic Disclosure and Barring Service (DBS) check.